Sökning: "Granuloma"

Visar resultat 1 - 5 av 35 avhandlingar innehållade ordet Granuloma.

  1. 1. Aspects of pertussis, pertussis vaccination and adverse events associated with aluminum adsorbed vaccines

    Författare :Elisabet Bergfors; Göteborgs universitet; []
    Nyckelord :Pertussis; parapertussis; pertussis toxoid; vaccine; vaccination; vaccine trial; adjuvant; aluminium; adsorbed vaccines; adverse event; pruritic nodules; itching nodules; granuloma; sensitisation; hypersensitivity; contact allergy;

    Sammanfattning : The thesis originates in a clinical study of one of the new acellular pertussis vaccines performed in Göteborg in the 1990s. The monocomponent vaccine, pertussis toxoid adsorbed to aluminium hydroxide, had previously been shown to have an efficacy of 71%. LÄS MER

  3. 2. Immunopathogenesis of schistosomiasis mansoni : Immunity and pathology in a primary and a secondary infection following chemotherapy in the mouse and the baboo models

    Författare :Idle Omar Farah; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Physiology and anatomy; Baboon; BALB c mice; Chemotherapy; Cytokines; Fibrosis; Granuloma; Modulation; Pathology; Reinfection; Schistosoma mansoni; Th1; Th2; Fysiologi och anatomi; Physiology and pharmacology; Fysiologi och farmakologi; Medicine; medicin;

    Sammanfattning : This thesis describes a series of experiments aimed at elucidating the mechanisms ofimmunity and pathology elicited by both a primary infection and a reinfection exposure toSchistosoma mansoni following chemotherapy. The effects of a single large cercarial doseand a cumulatively equivalent dose, administered as multiple small doses are compared. LÄS MER

  4. 3. Clinical studies of contact granuloma and posterior laryngitis with special regard to esophagopharyngeal reflux

    Författare :Riitta Ylitalo; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :contact granuloma; surgical treatment; voice therapy; voice quality; perceptual analysis; acoustic analysis; posterior glottis; posterior laryngitis; recurrence frequency; esophagopharyngeal reflux; pH monitoring; manometry;

    Sammanfattning : This investigation had two main goals. The first goal was to evaluate the clinical symptoms and signs of contact granuloma patients and to study the short-and long-term treatment outcomes. LÄS MER

  5. 4. Local immune responses in tuberculosis : cytolytic effector functions at the site of mycobacterium tuberculosis infection

    Författare :Sayma Rahman; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Despite recent advances in tuberculosis (TB) research, shortage of knowledge still exists that limits the host-pathogen interactions in human TB. Cell-mediated immunity has been shown to confer protection in TB, although the relative importance of cytolytic T cells (CTLs) expressing granule-associated effector molecules perforin and granulysin is debated. LÄS MER

  7. 5. Studies of immune response in human tuberculosis

    Författare :Senait Ashenafi; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : TB (tuberculosis), caused by Mycobacterium tuberculosis (Mtb), continues to be a world-leading killer and a serious global health problem primarily affecting poor people in many developing countries. The difficult situation with TB/HIV co-infection is also a major key challenge to public health. LÄS MER