Sökning: "lung ventilation"

Visar resultat 21 - 25 av 128 avhandlingar innehållade orden lung ventilation.

  1. 21. Titrating Open Lung PEEP in Acute Lung Injury : A clinical method based on changes in dynamic compliance

    Författare :Fernando Suarez Sipmann; Göran Hedenstierna; Hans Hedenström; Stefan Lundin; Uppsala universitet; []
    Nyckelord :LANTBRUKSVETENSKAPER; AGRICULTURAL SCIENCES; PEEP; open lung; recruitment; dead space; electrical impedance tomography; ARDS.; Medicine; Medicin;

    Sammanfattning : The recognition that supportive mechanical ventilation can also damage the lung, the so called ventilation induced lung injury (VILI), has revived the more than 40 year long debate on the optimal level of PEEP to be used. It is established that the prevention of VILI improves patient outcome and that PEEP exerts protective effects by preventing unstable diseased alveoli from collapsing. LÄS MER

  2. 22. Benefits of Spontaneous Breathing : Compared with Mechanical Ventilation

    Författare :László Vimláti; Michael Lichtwarck-Aschoff; Anders Larsson; Lars Wiklund; Carl-Johan Wickerts; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; spontaneous breathing; mechanical ventilation; pulmonary shunt; oxygenation; hypoxic pulmonary vasoconstriction; Anestesiologi och intensivvård; Anaesthesiology and Intensive Care;

    Sammanfattning : When spontaneous breathing (SB) is allowed during mechanical ventilation (MV), atelectatic lung areas are recruited and oxygenation improves thereby. Whether unsupported SB at its natural pattern (without PEEP and at low pressure/small tidal volume) equally recruits and improves oxygenation, and if so by which mechanism, has not been studied. LÄS MER

  3. 23. Lung and chest wall properties during mechanical ventilation

    Författare :Per Erik Persson; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Mechanical ventilation; Respiratory mechanics; Esophageal pressure; Positive end-expiratory pressure;

    Sammanfattning : Background: Mechanical ventilation causes injury to the lungs due to high pressures and high volumes. Pressure affecting the lungs, the transpulmonary pressure, needs to be monitored to minimise harmful side effects but then lung and chest wall mechanics need to be separately considered. LÄS MER

  4. 24. FRC in acute lung injury. Experimental and clinical studies

    Författare :Christian Rylander; Göteborgs universitet; []
    Nyckelord :Airway obstruction; Acute lung injury; Acute respiratory distress syndrome; Attenuation; Computed tomography; End-expiratory lung volume; Functional residual capacity; Gas dilution; Hounsfield unit; Lung volume; Oleic acid; Recruitment; Time constant;

    Sammanfattning : Respiratory failure due to acute lung injury (ALI) of diffuse inflammatory origin is a major cause of respiratory failure treated in intensive care units. In ALI, FRC is reduced by various mechanisms associated with hypoxemia and consolidation of the lung. LÄS MER

  5. 25. Endothelin receptor changes during inflammation in the lung

    Författare :Bengt Granström; Lund Pediatrik; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Andningsorganen; Respiratory system; Upregulation; Smooth muscle cells; Smoking; Sephadex; Remodeling; Rat; mRNA; Human; ETB receptor; ETA receptor; Lung; Endothelin; Asthma bronchiale; Contraction;

    Sammanfattning : Endothelin-1 (ET-1) is an extremely potent smooth muscle spasmogen well known from the vascular system but also active within the airways. The importance of its proinflammatory and co-mitogenic properties has become increasingly evident, the endothelin system also having been shown to mimic the signal features of asthma, COPD and other pulmonary diseases. LÄS MER