Sökning: "isoform"

Visar resultat 1 - 5 av 306 avhandlingar innehållade ordet isoform.

1. 1. Membrane-Assisted Isoform ImmunoAssay : Separation and determination of protein isoforms

   Författare :Maria Lönnberg; Carl G M Magnusson; Uppsala universitet; []
   Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Biotechnology; Bioteknik; Bioengineering; Bioteknik; Surface Biotechnology; ytbioteknik;

   Sammanfattning : Proteins exist in a variety of isoforms with minor differences, mostly due to their glycosylation patterns, which can modulate their biological functions. It seems to be of clinical relevance to measure the isoform-distribution.Thesis describes a novel technology named Membrane-Assisted Isoform ImmunoAssay (MAIIA). LÄS MER

3. 2. Plant Calreticulins - isoforms, localization and function

   Författare :Karin Svensson; Biologiska institutionen; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; arabidopsis thaliana; calcium; isoform; endoplasmic reticulum; chaperone; tunicamycin;

   Sammanfattning : Calreticulin (CRT) is an endoplasmic reticulum (ER)-located protein involved in quality control of newly synthesized proteins as well as in calcium homeostasis of the cell. Most of what is known about CRT arises from studies of mammalian systems. LÄS MER

4. 3. Mass spectrometry for comparative proteomics of degenerative and regenerative processes in the brain

   Författare :Carina Sihlbom; Göteborgs universitet; []
   Nyckelord :glycoproteomics; quantitative proteomics; glycoprotein; protein quantification; glycosylation; Fourier transform ion cyclotron mass spectrometry; cerebrospinal fluid; Alzheimer s disease; neurodegeneration; neuroregeneration; hippocampus; astrocytes; brain injury; 14-3-3 protein; isoform;

   Sammanfattning : Biological processes involve changes at the protein level. Proteomics aims to determine protein changes from a normal state, to measure for instance recovery or disease progression. Mass spectrometry is the most important tool for identification of proteins and determination of post-translational modifications such as glycosylation. LÄS MER

5. 4. Peptidoglycan recognition proteins in Drosophila melanogaster

   Författare :Thomas Werner; Dan Hultmark; Bruno Lemaitre; Umeå universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Molecular biology; Drosophila; PGRP; peptidoglycan; pattern recognition; imd; Relish; isoform; RNAi; mbn-2; Molekylärbiologi; Molecular biology; Molekylärbiologi; molekylärbiologi; Molecular Biology;

   Sammanfattning : The fruit fly Drosophila melanogaster is an excellent model organism to study the innate immune response, because insects and mammals share conserved features regarding the recognition and destruction of microorganisms and Drosophila is easily accessible to genetic manipulation. In my present study, I identified a new family of pattern recognition molecules for bacterial peptidoglycan in Drosophila, the Peptidoglycan Recognition Proteins (PGRP). LÄS MER

7. 5. Proteome Profiling of Strawberry and Characterization of a Bet v 1-Homologous Allergen

   Författare :Rikard Alm; Biokemi och Strukturbiologi; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; metabolism; Biochemistry; Metabolism; Biokemi; Naturvetenskap; Plant biochemistry; Växtbiokemi; Respiratory system; Andningsorganen; Natural science; biomatematik; Bioinformatics; medical informatics; biomathematics biometrics; Bioinformatik; medicinsk informatik; speclust; proteios; biological variation; phenotypic plasticity; data management; DIGE; sequencing; isoform; allergen; Proteomics; strawberry;

   Sammanfattning : Strawberry (Fragaria ananassa) is an economically important crop, and recognised as an important source of antioxidants and bioactive compounds with health promoting effects. Yet increased incidence of allergy puts a limit to the choice of food for an increasing percentage of the population. LÄS MER