Sökning: "hantavirus"

Visar resultat 1 - 5 av 25 avhandlingar innehållade ordet hantavirus.

1. 1. TRANSMISSION AND PATHOGENESIS OF HANTAVIRUS

   Författare :Lisa Pettersson; Magnus Evander; Clas Ahlm; Annika Allard; Tatjana Avšič - Županc; Umeå universitet; []
   Nyckelord :Puumala virus; Hantavirus; human-to-human transmission; saliva; nephropathia epidemica; NE; IgA; IgG; IgM; neutrophils; neutrophil; viremia; treatment; climate; snow cover; temperature.; medicinsk virologi; Medical Virology;

   Sammanfattning : Hantaviruses are the causative agents of hemorrhagic fever with renal syndrome (HFRS) in Eurasia, and of hantavirus cardiopulmonary syndrome (HCPS) in the Americas. Transmission to humans usually occurs by inhalation of aerosolized virus-contaminated rodent excreta. LÄS MER

3. 2. Cardiopulmonary involvement in Puumala hantavirus infection

   Författare :Johan Rasmuson; Clas Ahlm; Anders Blomberg; Jamshid Pourazar; Gregory J. Mertz; Umeå universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Hemorrhagic fever with renal syndrome; hantavirus; echocardiography; respiratory function tests; computed tomography; bronchoalveolar lavage; biopsy; cytotoxic T cells; disease severity; Infectious Diseases; infektionssjukdomar;

   Sammanfattning : Puumala hantavirus (PUUV) causes hemorrhagic fever with renal syndrome in Europe. After inhalation of virus shed by bank voles, the virus systemically targets the vascular endothelium leading to vascular dysfunction and leakage. LÄS MER

4. 3. Genetic and serologic characterization of a Swedish human hantavirus isolate

   Författare :Marie Lindkvist; Göran Bucht; Clas Alhm; Per Juto; Rainer Ulrich; Umeå universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; hantavirus; puumalavirus; diagnostics; HFRS; nucleocapsid protein; B-cell epitopes; epitope-mapping; protein interactions; glycosylation; antibody response; cross-reactivity; Virology; Virologi;

   Sammanfattning : Hantaviruses are found practically all over the world and cause hemorrhagic fevers in man. Each year about 150,000 people are hospitalized in these zoonotic infections which can be of two types: hemorrhagic fever with renal syndrome (HFRS) or hantavirus cardiopulmonary syndrome (HCPS), depending on the infecting virus. LÄS MER

5. 4. Implications of Local Puumala Hantavirus Genetics and Epidemiology for Diagnostics and Vaccine Development

   Författare :Patrik Johansson; Fredrik Elgh; Göran Bucht; Detlev Krüger; Umeå universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Communicable diseases; hantavirus; Puumala virus; nephropathia epidemica; genome sequence; glycosylation; linear DNA vaccine; microarray; identification; genetic variability; Infektionssjukdomar; Infectious diseases; Infektionssjukdomar; medicinsk virologi; Medical Virology;

   Sammanfattning : Puumala viruses, a member of the Hantavirus genus in the Bunyaviridae family, are enveloped by a lipid bilayer and possesses a tripartite single stranded RNA genome with negative polarity. The hantaviruses encode four proteins: a nucleocapsid protein (N), two membrane spanning glycoproteins (GN and GC) and a RNA dependent RNA polymerase (RdRp). LÄS MER

7. 5. Study of pathogenesis and immune response in human Puumala virus infection

   Författare :Therese Thunberg; Clas Ahlm; Jonas Klingström; Brian Hjelle; Umeå universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Hantavirus; puumala virus; immune response; viral load; NK cells; T cells; cytokines; disease severity; Infectious Diseases; infektionssjukdomar;

   Sammanfattning : Hantaviruses can cause two severe human diseases: hemorrhagic fever with renal syndrome (HFRS) and hantavirus cardiopulmonary syndrome (HCPS). Hantaviruses are spread to humans mainly through inhalation of infectious virions, secreted from infected rodents. The human diseases are characterized by an increased capillary leakage syndrome. LÄS MER