Sökning: "viral load"

Visar resultat 1 - 5 av 152 avhandlingar innehållade orden viral load.

  1. 1. Human Papillomavirus Load and Cervical Carcinoma

    Författare :Martin Moberg; Ulf Gyllensten; Björn Hagmar; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Molecular biology; cervical cancer; human papillomavirus; viral load; HLA class II; Molekylärbiologi; Molecular biology; Molekylärbiologi;

    Sammanfattning : Human Papillomavirus (HPV) is a key factor in the development of cervical cancer. Out of the more than 100 known HPV types 13 are considered oncogenic. In addition to presence of the virus several other factors have been proposed to influence risk of cervical cancer. LÄS MER

  3. 2. Antiretroviral treatment of HIV-1 in Sweden with focus on virological aspects

    Författare :Erik Sörstedt; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; HIV-1; antiretroviral therapy; transient viremia; viral blip; nucleoside transcriptase inhibitor resistance; dolutegravir; baseline viral load; HIV RNA; virological failure;

    Sammanfattning : From a clinical standpoint, there are many factors to consider when optimizing the care for people living with HIV (PLWH). With help from clinical guidelines, most obstacles can be addressed. Expanded knowledge is however in constant demand, from local conditions to universal processes. LÄS MER

  4. 3. Evaluation of reverse transcriptase assay for viral load monitoring

    Författare :Gary E Corrigan; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Retaining an active reverse transcriptase (RT) enzyme is a fundamental requirement for all retroviruses to replicate. Bearing in mind that HIV has a very high propensity to mutate measuring RT activity to determine the level of retroviral replication has the capacity to eliminate problems associated with divergence, as the virus at all costs must retain an active RT enzyme. LÄS MER

  5. 4. Genetic Risk Factors for Cervical Carcinoma in situ

    Författare :Anna Beskow; Peter L Stern; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Genetics; Cervical carcinoma; human papillomavirus; viral load; long-term infection; HLA class II; p53; E6 variant; Genetik; Clinical genetics; Klinisk genetik; Medical Genetics; medicinsk genetik;

    Sammanfattning : Oncogenic human papillomaviruses (HPVs) are implicated in 99.7 % of cervical cancer cases but require the co-operation of other factors. To investigate potential genetic risk factors we have typed the HLA class II DRB1 and DQB1 loci in 478 women diagnosed with cervical carcinoma in situ and in 608 age-matched controls. LÄS MER

  7. 5. Low-level HIV viremia during antiretroviral therapy

    Författare :Olof Elvstam; Klinisk infektionsmedicin; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Human immunodeficiency virus; Viral load; Antiretroviral therapy; Mortality; Malignancies; Cardiovascular disease;

    Sammanfattning : In most cases, antiretroviral therapy (ART) results in undetectable plasma HIV viral load (VL). Still, up to 25% of ART recipients may have detectable low-level viremia (LLV) of different amplitude and persistence. This thesis explores the impact of LLV during ART on virologic and clinical outcomes. LÄS MER