Sökning: "neutrophil"

Visar resultat 1 - 5 av 399 avhandlingar innehållade ordet neutrophil.

1. 1. Neutrophil recruitment in periodontal disease

   Författare :Agnes Dahlstrand Rudin; Göteborgs universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; neutrophil; periodontitis; P. gingivalis; F. nucleatum; SCFA; FFAR2; CD177; A1AT;

   Sammanfattning : Neutrophils are the first immune cells to arrive in infected or injured tissues, where they engulf microbes and clean up cell debris. Periodontitis is one of the typical symptoms of both neutropenia and defect neutrophil functionality, suggesting an important role for these cells in maintenance of periodontal health. LÄS MER

3. 2. Neutrophil and endothelial cell-mediated inflammation in abdominal sepsis

   Författare :Zhiyi Ding; Kirurgi; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; sepsis; lung; neutrophil; endothelial cell; neutrophil extracellular traps; inflammation; capillary; post capillary venules; cytoskeleton; RNAseq;

   Sammanfattning : Sepsis is defined as a life-threatening condition caused by a dysregulated host response to infection. Neutrophils are themost abundant innate immune cells of the body and play a key role in septic pathogenesis. LÄS MER

4. 3. Neutrophil chemotaxis. Analyses of neutrophil chemotaxis i a new fluid gradient chamber

   Författare :Reza Ebrahimzadeh Pirshahid; Göteborgs universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Cell movement; Chemotaxis; Leukocyte; Neutrophil; Human; Filter; Methods; N-Formylmethionine-Leucyl-Phenylalanine; Normal distribution; Partial differential equation;

   Sammanfattning : The leukocytes have, as part of their function in immune system, the ability to leave the bloodstream, penetrate the vascular wall and migrate towards extravascular targets. This behaviour of the leukocytes has been extensively studied both in vivo and in vitro since the 19th century but the mechanisms underlying leukocyte migration are not yet fully understood. LÄS MER

5. 4. CD64 (FcγRI) Expression on Neutrophil Granulocytes : A Diagnostic Marker of Acute Bacterial Infections

   Författare :Gustav Fjaertoft; Tony Foucard; Per Venge; Stelllan Håkansson; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Pediatrics; CD64; FcγRI; Neutrophil; Infection; Newborn; Neonate; Pediatrik; Paediatric medicine; Pediatrisk medicin;

   Sammanfattning : Background. Newborn infants, especially preterm infants, have an increased susceptibility to serious and overwhelming bacterial as well as fungal infections. Symptoms of septicaemia in especially the very preterm neonates are vague and unspecific. LÄS MER

7. 5. Novel findings on cellular trafficking and targeting for granule storage of neutrophil elastase, a multifunctional effector molecule of innate immunity

   Författare :Linda Källquist; Avdelningen för hematologi och transfusionsmedicin; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Hematopoietic cell; CD63; neutrophil elastase; targeting; trafficking; intracellular sorting; neutrophil; azurophil granule;

   Sammanfattning : Neutrophil elastase (NE) has important roles in innate immunity, killing pathogens and controlling the immune response; but how NE is targeted to developing granules is not understood. Therefore, the aim of this thesis was to investigate the sorting of NE. LÄS MER