Sökning: "generic cells"

Visar resultat 1 - 5 av 44 avhandlingar innehållade orden generic cells.

  1. 1. The immortalization process of T cells : with focus on the regulation of telomere length and telomerase activity

    Författare :Sofie Degerman; Göran Roos; John Sedivy; Umeå universitet; []
    Nyckelord :immortalization; senescence; T cells; Nijmegen breakage syndrome; telomere; telomerase; hTERT; generic aberrations; methylation; MEDICINE; MEDICIN; Pathology; patologi;

    Sammanfattning : Cellular immortalization is a major hallmark of cancer and is a multi-step process that requires numerous cell-type specific changes, including inactivation of control mechanisms and stabilization of telomere length. The telomeres at the chromosome ends are essential for genomic stability, and limit the growth potential of most cells. LÄS MER

  3. 2. On acoustic particle and cell manipulation in microfluidic systems

    Författare :Filip Petersson; Avdelningen för Biomedicinsk teknik; []
    Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Medicin människa och djur ; Natural science; Naturvetenskap; Technological sciences; Teknik; acoustic particle manipulation standing wave; acoustic radiation force; laminar flow; Medicine human and vertebrates ; microparticles; ultrasound; lab-on-a-chip; µ-TAS; separation; cells; microfabrication; microtechnology; microfluidics;

    Sammanfattning : The combination of laminar flows in microfabricated channels and acoustic forces induced in ultrasonic standing wave fields offers new possibilities for advanced particle and cell manipulation in lab-on-a-chip applications as well as in relatively high throughput applications. Acoustic particle manipulation systems can be used e.g. LÄS MER

  4. 3. Generic Properties of Polymer Solutions

    Författare :Takashi Uematsu; Chalmers tekniska högskola; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; photon correlation spectroscopy; collective diffusion; atomic force microscopy; relaxation; agarose gel electrophoresis; DNA; Zimm dynamics; pulsed-field gradient NMR; superdiffusion; polymer solution; blob model; gel;

    Sammanfattning : Polymer solutions are abundantly present in our daily life, for example in paints, jellies, contact lenses and even in the living cells. Despite their ubiquity, we still have a poor understanding of the physical properties of solutions due to the extremely large number of internal degrees of freedom. LÄS MER

  5. 4. Programmable and Tunable Circuits for Flexible RF Front Ends

    Författare :Naveed Ahsan; Aziz Ouacha; Sten Gunnarsson; Linköpings universitet; []
    Nyckelord :Microwave circuits; phase shifters; programmable circuits; active corporate feed network; four-port circuit; generic cells; phase shift capability; programmable microwave function array; tunable recursive filter; TECHNOLOGY; TEKNIKVETENSKAP;

    Sammanfattning : Most of today’s microwave circuits are designed for specific function and specialneed. There is a growing trend to have flexible and reconfigurable circuits. Circuitsthat can be digitally programmed to achieve various functions based on specific needs. LÄS MER

  7. 5. Genetic modification of human natural killer cells and possible applications thereof

    Författare :Kyriakos Konstantinidis; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Natural killer cells; retroviral transduction; interleukin-2; endoplasmic reticulum targeting; green fluorescent protein; multiple myeloma;

    Sammanfattning : Natural killer (NK) cells are dependent on the presence of interleukin-2 (IL-2) for their survival and for their cytotoxicity against tumor cells. Currently, for in vitro expansion of NK cells from peripheral blood mononuclear cells (PBMCs), IL-2 is of great importance. LÄS MER