Sökning: "decellularization"
Visar resultat 1 - 5 av 9 avhandlingar innehållade ordet decellularization.
1. Decellularization as a method to generate a new generation of vascular grafts
Sammanfattning : Decellularization of blood vessels is a technique to remove cells from the extracellular matrix (ECM), which can be used as a vascular graft for peripheral or coronary blood vessel bypass surgery. This thesis focuses on the optimization of decellularization strategies for blood vessels such as porcine vena cava, to determine the optimal decellularization protocol (Paper I) and the ideal method of applying liquids during the decellularization process (Paper II). LÄS MER
2. Potential Therapeutic Applications of Novel Bioengineered Tissues and Organs Using Methods of Decellularization and Recellularization
Sammanfattning : The transplantation of personalized organs or tissues will benefit patients with various diseases and disorders. Decellularization is a method to generate an acellular, non-immunogenic natural scaffold. LÄS MER
3. Principles of scaffold generation for bioengineering of the ovary and uterus: a study focusing on decellularization
Sammanfattning : Introduction: Cancer therapy often result in fertility problems due to inflicted injury to the reproductive organs. Since most women survive cancer, fertility preservation has become an important consideration during cancer therapy. However, options for young women with blood-related cancers are missing. LÄS MER
4. On tissue engineering of pig, human, and non-human primate tissues
Sammanfattning : Background: Demand for donor organs for transplantation has been increasing every year more than the actual supply of suitable donor organs. One of the major problems associated with allogeneic transplantation includes lifelong immunosuppression. LÄS MER
5. Tissue engineering for novel female infertillity treatments: studies on small and large animal models
Sammanfattning : Introduction: As with any transplantation (Tx) procedure, uterus Tx is associated with risky donor surgery and adverse side-effects from immunosuppression. With the aim to bypass these risks, this thesis investigated uterus tissue engineering strategies and the potential to develop a patient-specific uterus graft to replace the need for donor surgery and immunosuppression. LÄS MER