Sökning: "anti-viral"

Visar resultat 1 - 5 av 54 avhandlingar innehållade ordet anti-viral.

1. 1. Anti-parasitic and anti-viral immune responses in insects

   Författare :Olle Terenius; Ingrid Faye; Kenneth Söderhäll; Stockholms universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Hemolin; Hyalophora cecropia; Antheraea pernyi; Drosophila melanogaster; anti-viral; anti-parasitic; rna interference; microarray; innate immunity; Genetics; Genetik;

   Sammanfattning : Insects encounter many microorganisms in nature and to survive they have developed counter measures against the invading pathogens. In Drosophila melanogaster research on insect immunity has mainly been focused on infections by bacteria and fungi. LÄS MER

3. 2. Functional characterization of the human adenovirus pVII protein and non-coding VA RNAI

   Författare :Raviteja Inturi; Tanel Punga; Goran Akusjarvi; Thomas Dobner; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Adenovirus; VA RNA; protein VII; Ubiquitination; proteasome; anti-viral; Medical Biochemistry; Medicinsk biokemi; Mikrobiologi; Microbiology; Medical Virology; Medicinsk virologi;

   Sammanfattning : Human adenovirus (HAdV) is a common pathogen causing a broad spectrum of diseases. HAdV encodes the pVII protein, which is involved in nuclear delivery, protection and expression of viral DNA. To suppress the cellular interferon (IFN) and RNA interference (RNAi) systems, HAdVs encode non-coding virus-associated (VA) RNAs. LÄS MER

4. 3. On causes and regulation of anti-viral defence in asthma and COPD

   Författare :Mandy Menzel; Respiratorisk immunofarmakologi; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; asthma; chronic obstructive pulmonary disease; rhinovirus; exacerbation; airway epithelial cell; ; pattern recognition receptors; interferon; allergen; azithromycin; inflammasome; epithelial-derived cytokines; oxidative stress; asthma; chronic obstructive pulmonary disease; rhinovirus; exacerbation; airway epithelial cell; pattern recognition receptors; interferon; allergen; azithromycin; inflammasome; epithelial-derived cytokines; oxidative stress;

   Sammanfattning : Rhinovirus infection is a main trigger of asthma and COPD exacerbations. dsRNA, a viral replication intermediate, is sensed by pattern recognition receptors in the airway epithelium leading to down-stream induction of anti-viral interferons. LÄS MER

5. 4. Cellular and molecular mechanisms for induction of broad anti-viral B cell responses through vaccination

   Författare :Sebastian Ols; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :;

   Sammanfattning : Viral infections contribute to significant morbidity and mortality worldwide. The immense diversity across and within viral families poses a substantial challenge for the development of prophylaxis and therapeutics. Vaccines are one of the most effective medical interventions to prevent infectious diseases. LÄS MER

7. 5. Deoxyribonucleoside kinases in bacteria, plants and humans

   Författare :Anders Ranegaard Clausen; Biologiska institutionen; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; anti-viral drugs; gene therapy; cancer; evolution; nucleoside analog; deoxyribonucleoside kinase; thymidine kinase;

   Sammanfattning : Deoxyribonucleoside triphosphates (dNTPs) are the building blocks of DNA and can be synthesized either de novo or via salvage pathways. The first reaction in the salvage pathway of dNTPs is the conversion of deoxyribonucleosides (dN) into the deoxyribonucleoside monophosphate (dNMP). LÄS MER