Sökning: "SAH"

Visar resultat 6 - 10 av 43 avhandlingar innehållade ordet SAH.

  1. 6. Subarachnoid Hemorrhage in the Elderly

    Författare :Mats Ryttlefors; Per Enblad; Kristina Cesarini; David Mendelow; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; subarachnoid hemorrhage; intracranial aneurysm; elderly; outcome; endovascular coiling; neurosurgical clipping; secondary insult; cerebral vasospasm; Neurosurgery; Neurokirurgi;

    Sammanfattning : Subarachnoid hemorrhage (SAH) is a disease with high risk of mortality and morbidity. Elderly patients have an even higher risk of poor outcome. The incidence of SAH increases with age and the elderly constitute a substantial and increasing proportion of the population. Thus, the management of elderly SAH patients is an imminent clinical challenge. LÄS MER

  2. 7. Subarachnoid haemorrhage : clinical and epidemiological studies

    Författare :Cecilia Lindgren; Silvana Naredi; Magnus Hultin; Lars-Owe Koskinen; Elisabeth Ronne-Engström; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Subarachnoid haemorrhage; ADMA; Cortisol; EEG; inflammation; epidemiology; endothelium; arginine; anestesiologi; Anaesthesiology; neurokirurgi; Neurosurgery; epidemiologi; Epidemiology;

    Sammanfattning : Background: Subarachnoid haemorrhage (SAH) is a severe stroke that in 85% of all cases is caused by the rupture of a cerebral aneurysm. The median age at onset is 50-55 years and the overall mortality is approximately 45%.Sufficient cortisol levels are important for survival. LÄS MER

  3. 8. Metabolic and Endocrine Response in the Acute Stage of Subarachnoid Hemorrhage

    Författare :Christoffer Nyberg; Elisabeth Ronne Engström; Torbjörn Karlsson; Lars Hillered; Silvana Naredi; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Subarachnoid hemorrhage; Energy Expenditure; BNP; Animal Model; Cortisol; Microdialysis; Neurokirurgi; Neurosurgery;

    Sammanfattning : The rupture of an aneurysm in subarachnoid hemorrhage (SAH) is a dramatic event causing a severe impact on the brain and a transient or permanent ischemic condition. Several types of responses to meet the challenges of SAH have been found in the acute phase, including activation of the hypothalamic-pituitary-adrenal (HPA) axis and the sympathetic nervous system, elevated levels of brain natriuretic peptide (BNP), and disturbances in cerebral and systemic metabolism. LÄS MER

  4. 9. Protein Kinase Inhibition in Late Cerebral Ischemia after Subarachnoid Hemorrhage

    Författare :Saema Ansar; Lund Medicin; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Neurology; neuropsychology; neurophysiology; Neurologi; protein kinase; cerebral ischemia; subarachnoid hemorrage; neurofysiologi; neuropsykologi;

    Sammanfattning : The cerebral ischemia that occur after a subarachnoid hemorrhage (SAH) often results in death or severe disability and is a significant cause of stroke. Our hypothesis is that cerebral ischemia leads to pathophysiological receptor changes on the vascular smooth muscle cells. LÄS MER

  5. 10. Pathophysiology of subarachnoid hemorrhage in the rat

    Författare :Giselle F Prunell dos Santos; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Apoptosis; cell death; cerebral blood flow; cerebral metabolism; inflammation; NMDA receptor subunits; subarachnoid hemorrhage.;

    Sammanfattning : Subarachnoid hemorrhage (SAH) causes brain damage, but the underlying mechanisms are poorly understood. An obstacle in SAH research is the lack of an adequate animal model. In this thesis, we developed a new approach to simulate SAH that involves the injection of blood into the prechiasmatic cistern of the rat. LÄS MER