Sökning: "Lars Hillered"

Visar resultat 1 - 5 av 10 avhandlingar innehållade orden Lars Hillered.

  1. 1. Clinical Consequences of Axonal Injury in Traumatic Brain Injury

    Författare :Sami Abu Hamdeh; Niklas Marklund; Per Enblad; Lars Hillered; Andreas PhD Unterberg MD; Uppsala universitet; []
    Nyckelord :Traumatic brain injury; diffuse axonal injury; intracranial pressure; magnetic resonance imaging; amyloid-beta; tau; Neurokirurgi; Neurosurgery;

    Sammanfattning : Traumatic brain injury (TBI), mainly caused by road-traffic accidents and falls, is a leading cause of mortality. Survivors often display debilitating motor, sensory and cognitive symptoms, leading to reduced quality of life and a profound economic burden to society. LÄS MER

  3. 2. Delayed Cell Death after Traumatic Brain Injury : Role of Reactive Oxygen Species

    Författare :Fredrik Clausen; Lars Hillered; Tiit Mathiesen; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Neurosciences; Traumatic Brain Injury; Reactive oxygen species; Fluid percussion injury; Controlled cortical impact; weight drop injury; Extracellular-signal regulated kinase; apoptosis; free radical scavenging; morphology; functional outcome; Neurovetenskap; Neurology; Neurologi;

    Sammanfattning : Traumatic brain injury (TBI) is a leading cause of death and disability TBI survivors often suffer from severe disturbances of cognition, memory and emotions. Improving the treatment is of great importance, but as of yet no specific neuroprotective treatment has been found. LÄS MER

  4. 3. Cellular Reactions and Behavioral Changes in Focal and Diffuse Traumatic Brain Injury : A Study in the Rat and Mouse

    Författare :Sara Ekmark Lewén; Lars Hillered; Niklas Marklund; Anders Lewén; Mårten Risling; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Traumatic brain injury; Astrocytes; Inflammatory response; Multivariate concentric square field test; Morris water maze; Exploratory behavior; Risk taking; Functional outcome.; Neurosurgery; Neurokirurgi;

    Sammanfattning : Traumatic brain injury (TBI) is a severe condition and a major cause of death and disability. There is no pharmacological treatment available in clinical practice today and knowledge of brain injury mechanisms is of importance for development of neuroprotective drugs. LÄS MER

  5. 4. Plasticity and Inflammation following Traumatic Brain Injury

    Författare :Anders Hånell; Niklas Marklund; Lars Hillered; Nikolaus Plesnila; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Traumatic Brain Injury; plasticity; inflammation; Nogo receptor; EphA4; IL-1β; Neurosurgery; Neurokirurgi; Neuroscience; Neurovetenskap;

    Sammanfattning : Traumatic Brain Injury (TBI) mainly affects young persons in traffic accidents and the elderly in fall accidents. Improvements in the clinical management have significantly improved the outcome following TBI but survivors still suffer from depression, memory problems, personality changes, epilepsy and fatigue. LÄS MER

  7. 5. Molecular Characterization of Experimental Traumatic Brain Injury

    Författare :Charlotte Israelsson; Ted Ebendal; Lars Hillered; Anders Lewén; Henrik Hagberg; Uppsala universitet; []
    Nyckelord :Neurosciences; traumatic brain injury; transcripts; GeneChip; chemokine; inflammation; mouse brain; neuroprotection; neuronal injury; neuroregeneration; astrocytosis; Neurovetenskap;

    Sammanfattning : Traumatic brain injury (TBI) is the most common cause of mortality and disability in the younger (.... LÄS MER