Sökning: "Keratinocytes tissue engineering"
Visar resultat 1 - 5 av 7 avhandlingar innehållade orden Keratinocytes tissue engineering.
1. Keratinocytes in tissue engineering of human skin: invitro and in vivo studies
Sammanfattning : Full thickness wounds, such as deep burns, need restoration of both the dermal and epidermal layers of the skin. In normal wound healing, re-epithelialization occurs by migration and proliferation of keratinocytes from the wound edges and by differentiation of stem cells from remaining hair follicles. LÄS MER
2. Disease-causing Keratin Mutations and Cytoskeletal Dysfunction in Human Skin : In vitro Models and new Pharmacologic Strategies for Treating Epidermolytic Genodermatoses
Sammanfattning : Epidermolysis bullosa simplex (EBS) and epidermolytic ichthyosis (EI) are rare skin fragility diseases characterized by intra-epidermal blistering due to autosomal dominant-negative mutations in basal (KRT5 or KRT14) and suprabasal (KRT1 or KRT10) keratin genes, respectively. Despite vast knowledge in the disease pathogenesis, the pathomechanisms are not fully understood, and no effective remedies exist. LÄS MER
3. Recombinant spider silk for biomedical applications - from functionalizing surfaces of synthetic materials to in vitro modelling of tissues
Sammanfattning : Spider silk is a natural protein-based material known for its medicinal use and remarkable mechanical properties. Structures made thereof are both strong and elastic and have been shown to be favorable matrices for tissue engineering. LÄS MER
4. degradable electroactive polymers: Synthesis, Macromolecular architecture and scaffold design
Sammanfattning : Electrically conducting polymers induce specific cellular responses at the molecular level. One of the crucial limitations of the use of conducting polymers in tissue engineering is their inability to degrade. LÄS MER
5. In vitro and in vivo studies on biodegradable matrices for autotransplantation
Sammanfattning : Tissue engineering (TE), one of the most rapidly growing fields of life science, is an interdisciplinary area in which technical, biological and medical expertise co-fertilize on another with the ultimate aim of restoring, maintaining or improving tissues and/or organs. This purpose links TE closely to research concerning reconstructive plastic surgery. LÄS MER