Sökning: "Gerd Lärfars"

Hittade 4 avhandlingar innehållade orden Gerd Lärfars.

1. 1. Human polymorphonuclear granulocytes in inflammation : studies with an emphasis on nitric oxide

   Författare :Gerd Lärfars; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :Polymorphonuclear granulocytes; inflammation; nitric oxide; leukotrienes; tumor necrois factor; rheumatoid arthritis; interferon-gamma; chronic granulomatous disease;

   Sammanfattning : The function of the polymorphonuclear neutrophil granulocyte (PMN) is of vital importance in inflammation. For the defense against infections PMNs are armored with different weapons such as chemotaxis, phagocytosis and production of cytotoxic substances. LÄS MER

3. 2. Two worlds, one goal : A Clinician’s Perspective on Laboratory Analyses in Anticoagulant Treatment

   Författare :Kerstin Arbring; Tomas Lindahl; Srinivas Uppugunduri; Margareta Holmström; Gerd Lärfars; Linköpings universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Anticoagulants; Warfarin; DOAC; PT-INR; VKORC1;

   Sammanfattning : Almost precisely a century ago, in the 1920s and 1930s, cattle bled to death in North America after being fed moldy hay containing sweet clover, the yellow Melilotus officinalis, and the white Melilotus albus. The toxic substance in the hay inhibiting blood coagulation was identified and named dicumarol. LÄS MER

4. 3. Epidemiology of venous thromboembolism with focus on risk markers

   Författare :Magdalena Johansson; Lars Johansson; Marcus Lind; Jan-Håkan Jansson; Gerd Lärfars; Umeå universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Venous thromboembolism; venous thrombosis; deep vein thrombosis; pulmonary embolism; incidence; risk markers; diabetes; glucose; alcohol consumption; alcohol dependence; physical activity; medicin; Medicine;

   Sammanfattning : Background: Venous thromboembolism (VTE) is a vascular disease with an incidence of approximately 140 cases per 100,000 person-years in adults. The incidence of VTE has increased over the last decades, and more than 20% of affected individuals die in the first year after diagnosis. LÄS MER

5. 4. Efficacy and safety of warfarin treatment in venous thromboembolic disease

   Författare :Per Sandén; Anders Själander; Peter Svensson; Gerd Lärfars; Umeå universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Warfarin; Venous thromboembolism; Bleeding;

   Sammanfattning : BackgroundAs a major cause of morbidity and mortality treatment of venous thromboembolism is important, with the correct use of anticoagulants it is possible to greatly reduce both mortality and morbidity. Warfarin is among the most widely used anticoagulants being effective in treatment and prevention of venous thromboembolism with few negative side effects other than bleeding complications. LÄS MER