Sökning: "Gastric fluid"

Visar resultat 1 - 5 av 18 avhandlingar innehållade orden Gastric fluid.

1. 1. Carbonate Ions and Gastric Cancer

   Författare :Roy Ehrnström; Malmö Patologi; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Medicine human and vertebrates ; ODC; COX-2; inflammation; Wistar rats; duodenogastric reflux; Medicin människa och djur ; proliferation; gastrojejunostomy; carbonate ions; Experimental gastric cancer;

   Sammanfattning : Nearly one million new cases of gastric cancer are diagnosed annually throughout the world. Even though the incidence has fallen dramatically in recent decades, this disease is still the second leading cause of cancer death in a global perspective. LÄS MER

3. 2. Investigation and Prediction of Small Intestinal Precipitation of Poorly Soluble Drugs : a Study Involving in silico, in vitro and in vivo Assessment

   Författare :Sara Carlert; Hans Lennernäs; Bertil Abrahamsson; Patrick Augustijns; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; gastrointestinal precipitation; crystallization; crystal nucleation; crystal growth; classical nucleation theory; poorly soluble drugs; drug absorption; biopharmaceutics classification system; in vitro in vivo correlations IVIVC ; in silico prediction; human intestinal fluid; dog intestinal fluid; simulated intestinal fluid; Biofarmaci; Biopharmaceutics;

   Sammanfattning : The main objectives of the present project were to increase the understanding of small intestinal precipitation of poorly soluble pharmaceutical drugs, investigate occurrence of crystalline small intestinal precipitation and effects of precipitation on absorption. The aim was to create and evaluate methods of predicting crystalline small intestinal drug precipitation using in vivo, in vitro and in silico models. LÄS MER

4. 3. Impact of the upper gut on body fluid regulation and blood pressure in man - potential involvement of a locally expressed renin-angiotensin system

   Författare :Peter Hallersund; Göteborgs universitet; []
   Nyckelord :angiotensin; stomach; duodenum; sodium; salt; diuresis; appetite; gastric bypass; blood pressure;

   Sammanfattning : This thesis explores the role of the upper gut in the regulation of diuresis and blood pressure control in relation to the novel finding of a mucosa-located renin-angiotensin system (RAS). RAS is a regulatory super-system vital for body fluid homeostasis and blood pressure control. LÄS MER

5. 4. Gastroduodenal epithelial transport in patients with cystic fibrosis

   Författare :Karin Edshage Hallberg; Göteborgs universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Cystic fibrosis; CFTR; intestinal motility; gastric secretion; IgA; Ussing chamber; intestinal permeability; genotype;

   Sammanfattning : Cystic fibrosis (CF) is an inherited disease where respiratory failure due to chronic lung infection is the major cause of death. A defective protein, cystic fibrosis transmembrane conductance regulator (CFTR) alters chloride epithelial transport. LÄS MER

7. 5. Influence of inflammation and of stage of lung development on the development of neonatal lung injury

   Författare :Erica Bäckström; Göteborgs universitet; []
   Nyckelord :premature birth; BPD; inflammation; IL-1β; lung development; gastric aspirates;

   Sammanfattning : Bronchopulmonary dysplasia (BPD) is a major cause of mortality and long-term morbidity in prematurely born infants. Pulmonary inflammation, and abnormal alveolar and vascular development of the lung are histological characteristics of BPD. Interleukin (IL)-1β is a central cytokine in inflammation. LÄS MER