Sökning: "Epithelial repair"

Visar resultat 11 - 15 av 50 avhandlingar innehållade orden Epithelial repair.

  1. 11. Studies on the interaction of human cells with transplantable materials for skin repair and cardiovascular surgery

    Författare :Katarina Jansson; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Cell culture; Keratinocytes; Fibroblasts; Endothelial cells; Reepithelialization; In vitro endothelialization; Tissue engineering; Biomaterial: Dermal substitute; Synthetic vascular graft; Heart valve bioprosthesis;

    Sammanfattning : Tissue engineering is becoming an important field for the development of new tissues in vitro for replacement of diseased or worn out parts of the body. This thesis describes some characteristics of cultured human cells seeded on transplantable materials for skin repair and cardiovascular surgery. LÄS MER

  3. 12. Human embryonic stem cells for retinal repair : preclinical in vitro and in vivo studies for the treatment of age-related macular degeneration with human embryonic stem cell-derived retinal pigment epithelial cells

    Författare :Sandra Petrus-Reurer; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Age-related macular degeneration (AMD) is the major cause of vision loss in the industrialized countries in people above sixty years of age. The dry advanced form of the disease, also termed as geographic atrophy (GA), is characterized by the progressive death of retinal pigment epithelial cells (RPE) and consequent loss of the adjacent photoreceptor (PR) layer, leading to an impaired visual function. LÄS MER

  4. 13. Saliva: a cell suspension of epithelial cells harboring the antimicrobial peptide LL-37 and the growth factor EGF

    Författare :Alexandra Aidoukovitch; Institutionen för experimentell medicinsk vetenskap; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Saliva; Oral health; Innate immunity; Cathelicidin; LL-37; Host defense peptides; EGF; Saliva; Oral health; Innate immunity; Cathelicidin; LL-37; Host defence peptides; EGF;

    Sammanfattning : Saliva plays a crucial role in maintaining oral health through its physical and chemical properties that provide various protective functions. One of its essential components is the human host defense peptide LL-37, which is produced by immune cells and epithelial cells, and participates in the first line of defense against pathogens. LÄS MER

  5. 14. The human antimicrobial protein hCAP18/LL37 in wound healing and cell proliferation

    Författare :Johan Heilborn; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Innate immunity; antimicrobial peptides; LL-37; epithelial cell; keratinocytes; proliferation; reepithelialization; wound healing; tissue repair; angiogenesis; tumor growth; vitamin D;

    Sammanfattning : Epithelia constitute the principal barriers separating the host and the potentially injurious environment, and defence of this interface is therefore essential. Antimicrobial peptides are key effector molecules of the innate immune system. LÄS MER

  7. 15. RNA-binding proteins in transcription and genome integrity

    Författare :Chiara Pederiva; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : For decades, it was believed that RNA was merely an intermediate step between DNA and protein effectors. It is now appreciated that RNA is an extremely versatile molecule that affects almost every aspect inside a cell. LÄS MER