Sökning: "Epithelial repair"

Visar resultat 16 - 20 av 50 avhandlingar innehållade orden Epithelial repair.

  1. 16. Not just a pipe's dream : plumbing the contribution of cell diversity to oesophageal homeostasis

    Författare :David Grommisch; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Epithelial barrier tissues like the skin, intestine, and oesophagus form a physical barrier that protects our body from external threats. To accurately fulfil their function, epithelial barriers are subject to constant epithelial cell renewal throughout our lifespan. LÄS MER

  2. 17. Vitamin A regulated neuronal regeneration and homeostasis

    Författare :Sofia Håglin; Anna Berghard; Staffan Bohm; Leif Carlsson; Ola Hermanson; Umeå universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Activity dependent; Adult stem cells; Ageing; CYP26B1; Homeostasis; Metaplasia; Neurogenesis; Olfactory epithelium; Regeneration; Respiratory epithelium; Retinoic acid; Sensory map; Vitamin A;

    Sammanfattning : The olfactory epithelium is a dynamic tissue maintained by continuous neurogenesis throughout life. Upon injury, neurons and other olfactory cell types are regenerated through proliferation of horizontal stem cells. Some genes that regulate vitamin A metabolism are spatially expressed in the olfactory epithelium. LÄS MER

  3. 18. Intracellular signaling in the lung : a role for C/EBP transcription factors in chronic obstructive pulmonary disease, glucocorticoid signaling and lung development

    Författare :Lukas Didon; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Over the last decade, a previously unknown role has been established for members of the C/EBP transcription factor family in lung gene expression. In other organs, C/EBPs are well known regulators of cell differentiation and linked processes such as proliferation, apoptosis, gene expression as well as central regulators of inflammatory responses and infectious defenses. LÄS MER

  4. 19. The role of angiopoietin-like 4 in inflammation

    Författare :Terri Phua; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Inflammation is a homeostatically fundamental feature of the host defence surveillance system made up of an army of sentinel cells that guard against foreign intrusion. At the onslaught of an attack, primary immune responders (macrophages and neutrophils) secrete a plethora of cytokines and chemokines that attract secondary responders (T and B cells) to the site of inflammation, to eliminate the intrusion and encourage tissue healing. LÄS MER

  5. 20. Oxidoreductases and RNA degradosome controlling virulence-associated traits of Salmonella enterica serovar Typhimurium

    Författare :Naeem Anwar; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : The oxidative stress response is a fundamental and primitive mode of innate immune defense in nearly all forms of life. The host oxidative stress response becomes truly important and effective especially against intracellular pathogens such as Salmonella. Pathogens have evolved diverse mechanisms to withstand the oxidative responses. LÄS MER