Sökning: "Bacterial analysis"

Visar resultat 1 - 5 av 464 avhandlingar innehållade orden Bacterial analysis.

  1. 1. Towards Anti-Virulence Antimicrobials, Discovery and Development of Sortase A Inhibitors and Investigations of Bacterial Phenotypes

    Författare :Patrick M. Wehrli; Göteborgs universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Sortase A; SrtA; Inhibitors; Anti-virulence; Bacterial analysis; FTIR spectroscopy; Bacterial phenotyping; Design of Experiment; Multivariate Data Analysis; PCA; ToF-SIMS; Time-of-flight secondary-ion-mass-spectrometry; Lipid analysis; ppGpp; Stringent response;

    Sammanfattning : Antibiotic resistance is an emerging and serious threat to public health. Immediate actions are required to preserve current antibiotics while intensifying research efforts towards the development of new effective therapeutics. LÄS MER

  3. 2. Bacterial antibody hydrolyzing enzymes – as bacterial virulence factors and biotechnological tools

    Författare :Eleni Bratanis; Infektionsmedicin; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Immunoglobulins; Immunomodulation; Antibody mediated immunity; Glycosylation; Bacterial virulence; Bacterial enzymes; Biotechnology; streptococcus pyogenes; Bdellovibrio bacteriovorus;

    Sammanfattning : Antibodies are an essential part of the human immune system, and antibody mediated immunity has been an area of interest for many researchers for almost a century. An accumulation of knowledge regarding antibody structure, glycosylation and receptor interactions has contributed to the current understanding of antibody mediated immunity. LÄS MER

  4. 3. Bacterial meningitis in children : clinical aspects and preventive effects of vaccinations

    Författare :Urban Johansson Kostenniemi; Sven-Arne Silfverdal; Christer Mehle; Hans Fredlund; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Bacterial meningitis; children; vaccination; clinical presentation; decision support techniques; disease management; risk assessment; disabilities; neurodevelopmental disorders; psychiatric disease; pediatrik; Pediatrics; Infectious Diseases; infektionssjukdomar;

    Sammanfattning : Bacterial meningitis, one of the most severe infections a child can contract, can be caused by several different strains of bacteria. Most commonly, Haemophilus influenzae type b (Hib), Streptococcus pneumoniae and Neisseria meningitidis. LÄS MER

  5. 4. Omics Data Analysis of Complex Diseases and Traits

    Författare :Saman Hosseini Ashtiani; Arne Elofsson; Dirk Repsilber; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Omics data; RNA-seq; Microarrays; Metabolomics; Network analysis; Psoriasis; E. coli; Hip osteoporosis; Lung adenocarcinoma; Spearman s correlation coefficient; LC-MS; PCA; DEG; PPI; biokemi med inriktning mot bioinformatik; Biochemistry towards Bioinformatics;

    Sammanfattning : Following the advent of the high-throughput techniques for producing massive omics data, new possibilities and challenges have also emerged in different fields of biology and medicine. Dealing with such data on different scales with different scopes such as genomics, transcriptomics, proteomics and metabolomics, demands appropriate data collection, preprocessing, statistical analysis, interpretation and visualization. LÄS MER

  7. 5. Synthesis and analysis of carbohydrates related to bacterial polysaccharides

    Författare :Hani Mobarak; Göran Widmalm; Ulf Nilsson; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; carbohydrates; synthesis; conformation; NMR; O-antigen; computer-assisted structure elucidation; Organic Chemistry; organisk kemi;

    Sammanfattning : The outer surface of bacteria is composed of around 75% carbohydrates, which are vital for the bacteria to survive and communicate with the host biological system. The thesis discusses different properties of carbohydrates that are essential for understanding the bacterial behavior in biological systems. LÄS MER