Sökning: "O-antigen"

Visar resultat 1 - 5 av 32 avhandlingar innehållade ordet O-antigen.

  1. 1. Structural Studies of O-antigen polysaccharides, Synthesis of 13C-labelled Oligosaccharides and Conformational Analysis thereof, using NMR Spectroscopy

    Författare :Ulrika Olsson; Göran Widmalm; Corine Sandström; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NMR spectroscopy; conformation; Escherichia coli; lipopolysaccharide; O-antigen; carbohydrates; structure; isotopic labelling; Organic chemistry; Organisk kemi; Organic Chemistry; organisk kemi;

    Sammanfattning : In order to understand biological processes, to treat and diagnose diseases, find appropriate vaccines and to prevent the outbreak of epidemics, it is essential to obtain more knowledge about carbohydrate structures. This thesis deals with structure and conformation of carbohydrates, analysed by NMR spectroscopy and MD simulations. LÄS MER

  2. 2. The synthesis of some Salmonella O-antigen specific glycosides

    Författare :Birgitta Gotthammar; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES;

    Sammanfattning : .... LÄS MER

  3. 3. Structure elucidation of O-antigen polysaccharides from Escherichia coli

    Författare :Mona Svensson; Göran Widmalm; Roland Stenutz; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Organic chemistry; Organisk kemi;

    Sammanfattning : .... LÄS MER

  4. 4. Exploring the Molecular Behavior of Carbohydrates by NMR Spectroscopy : Shapes, motions and interactions

    Författare :Olof Engström; Göran Widmalm; Anthony S. Serianni; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NMR spectroscopy; NMR relaxation; DNMR; CORCEMA-ST; carbohydrates; caffeine; O-antigen; glycofullerenes; organisk kemi; Organic Chemistry;

    Sammanfattning : Carbohydrates are essential biomolecules that decorate cell membranes and proteins in organisms. They are important both as structural elements and as identification markers. Many biological and pathogenic processes rely on the identification of carbohydrates by proteins, thereby making them attractive as molecular blueprints for drugs. LÄS MER

  5. 5. Synthesis and analysis of carbohydrates related to bacterial polysaccharides

    Författare :Hani Mobarak; Göran Widmalm; Ulf Nilsson; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; carbohydrates; synthesis; conformation; NMR; O-antigen; computer-assisted structure elucidation; Organic Chemistry; organisk kemi;

    Sammanfattning : The outer surface of bacteria is composed of around 75% carbohydrates, which are vital for the bacteria to survive and communicate with the host biological system. The thesis discusses different properties of carbohydrates that are essential for understanding the bacterial behavior in biological systems. LÄS MER