Sökning: "vasculitis"

Visar resultat 21 - 25 av 50 avhandlingar innehållade ordet vasculitis.

  1. 21. Immunopathogenesis of experimental Chagas' disease

    Författare :Dan Sunnemark; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Trypanosoma cruzi; Chagas disease; pathology; cytokines; vasculitis; atherosclerosis;

    Sammanfattning : Chagas' disease is a serious, life-threatening disease caused by the protozoan parasite Trypanosoma cruzi in South and Central America. Neither vaccine candidate(s) nor efficient, nontoxic chemotherapeutical agents exist at the present time. LÄS MER

  3. 22. The role of granulocyte antibodies in monocyte and granulocyte activation

    Författare :Agneta Wikman; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :ANCA; adhesion molecules; CD11b; CD62L; granulocyte antibodies; granulocytes; monocytes; systemic vasculitis;

    Sammanfattning : Granulocytes and monocytes are important cells during the first phase of inflammation. They are activated and recruited from the blood vessels to inflammatory sites via the regulation of receptors involved in adhesion to endothelium. LÄS MER

  4. 23. Studies of T cells in health and disease : receptor usage and cytokine expression

    Författare :Eva Halapi; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :T cell receptor; oligoclonal expansion Tumour-infiltrating Iymphocyte; Ovarian carcinoma; Interleukin 10; Multiple Myeloma; Systemic vasculitis; HLD DR0401*CDR3; HIV-I;

    Sammanfattning : T Iymphocytes are crucial components for the initiation and maintenance of an immune response. To identify and characterize different T cells and their antigen specific receptors has important bearing for the understanding of underlying mechanisms in immunopathological processes and also to allow for the design of therapeutic therapies to be used for modulation of immune responses. LÄS MER

  5. 24. Mechanisms of endothelial cell dysfunction in Wegener's granulomatosis

    Författare :Carolina Holmén; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Wegener´s granulomatosis; vasculitis; anti-endothelial cell antibody; circulating endothelial cell; vascular adhesion protein 1; MHC class-I related chain A;

    Sammanfattning : Vasculitides are a heterogeneous group of disorders that share a common feature of blood vessel inflammation. A major cell type of the blood vessel affected is the endothelial cell (EC). LÄS MER

  7. 25. Clinical and Epidemiological Studies of Wegener´s Granulomatosis

    Författare :Ann Knight; Roger Hällgren; Johan Askling; Anders Ekbom; Lennart Jacobsson; Uppsala universitet; []
    Nyckelord :Medicine; Wegener´s granulomatosis; incidence; time-trends; ANCA; familial aggregation; cancer risks; bladder cancer; cyclophosphamide; Medicin;

    Sammanfattning : Wegener´s granulomatosis (WG) is an unusual, serious, systemic vasculitis with specific clinical findings. The studies in this thesis aim at broadening our understanding of the aetiology and outcome of WG.Patients with WG were identified in the In-patient Register 1975-2001. LÄS MER