Sökning: "utvecklingsbiologi"

Visar resultat 31 - 35 av 255 avhandlingar innehållade ordet utvecklingsbiologi.

  1. 31. Vertebrate remains from the Upper Silurian-Lower Devonian of North Greenland

    Författare :Henning Blom; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Developmental biology; Utvecklingsbiologi;

    Sammanfattning : .... LÄS MER

  2. 32. Transcriptional and epigenetic control of gene expression in embryo development

    Författare :Ann Boija; Mattias Mannervik; Jerry L. Workman; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Epigenetics; Cell specification; Drosophila embryo; Dorsal morphogen; CBP p300; Gene regulation; Chromatin; Promoter proximal Pol II pausing; utvecklingsbiologi; Developmental Biology;

    Sammanfattning : During cell specification, temporal and spatially restricted gene expression programs are set up, forming different cell types and ultimately a multicellular organism. In this thesis, we have studied the molecular mechanisms by which sequence specific transcription factors and coactivators regulate RNA polymerase II (Pol II) transcription to establish specific gene expression programs and what epigenetic patterns that follows. LÄS MER

  3. 33. Rates and Patterns of Mutation in Microsatellite DNA

    Författare :Jesper Brohede; Christian Schlötterer; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Developmental biology; Utvecklingsbiologi; Developmental biology; Utvecklingsbiologi; evolutionär genetik; evolutionär genetik;

    Sammanfattning : Sequence comparisons of orthologous microsatellite loci in cattle and sheep revealed that the substitution rate in microsatellite flanking sequences does not differ from the rate in presumably neutrally evolving intron sequences. This suggests that microsatellites are generally located in regions that are not subjected to selection. LÄS MER

  4. 34. DNA double-strand break repair in ascomycetes

    Författare :Jiang Chen; Stefan Åström; Michael Lisby; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; utvecklingsbiologi; Developmental Biology;

    Sammanfattning : Nonhomologous end joining (NHEJ) and homologous recombination (HR) are two pathways for DNA double strand break (DSB) repair. We found that the NHEJ protein Nej1 interacted physically with the HR protein Srs2, which was dependent on phosphorylation of Nej1 by Dun1. Srs2 recruitment to a DSB partly relied on Nej1 and Dun1. LÄS MER

  5. 35. Regulators of chromatin and transcription in Drosophila

    Författare :Filip Crona; Mattias Mannervik; Fernando Azorin; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Transcription; chromatin; co-regulators; CBP; lysine demethylase; KDM4A; Brakeless; Drosophila; utvecklingsbiologi; Developmental Biology;

    Sammanfattning : Development of multicellular organisms is achieved by organized temporal and spatial patterns of gene expression leading to cell differentiation. Chromatin regulators control how the DNA is utilized by altering access of proteins to DNA and thereby function as co-factors in transcription. LÄS MER