Sökning: "somatic marker"

Visar resultat 1 - 5 av 27 avhandlingar innehållade orden somatic marker.

  1. 1. Telomere length : dynamics and role as a biological marker in malignancy

    Författare :Ulrika Svenson; Göran Roos; Uwe Martens; Umeå universitet; []
    Nyckelord :Telomere length; peripheral blood; immune cells; breast cancer; renal cell carcinoma; biological marker; patologi; Pathology;

    Sammanfattning : Telomeres are protective structures at the end of our chromosomes, composed of multiple repeats of the DNA sequence TTAGGG. They are essential for maintaining chromosomal stability by preventing damage and degradation of the chromosome ends. LÄS MER

  3. 2. New markers of bulk milk quality in relation to mastitis : studies on polymorphonuclear leukocytes and α-lactalbumin

    Författare :Erik Wickström; Sveriges lantbruksuniversitet; Sveriges lantbruksuniversitet; []
    Nyckelord :LANTBRUKSVETENSKAPER; AGRICULTURAL SCIENCES;

    Sammanfattning : All dairy processors depend on a continuous supply of high-quality bulk milk from milk producers to be able to distribute liquid milk and dairy products. Mastitis, inflammation of the bovine udder, is the most common disease in dairy cows, and leads to altered milk composition and impaired milk quality. LÄS MER

  4. 3. Genetic Alterations and Molecular Signatures in Aldosterone Producing Adenomas

    Författare :Tobias Åkerström; Peyman Björklund; Tracy Ann Williams; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Aldosterone; aldosterone producing adenoma; KCNJ5; ATP1A1; ATP2B3; CACNA1D; CTNNB1;

    Sammanfattning : Primary Aldosteronism (PA) is caused by autonomous overproduction of aldosterone. Aldosterone is necessary for fluid and ion homeostasis. Aberrant overproduction leads to hypertension and cardiovascular damage. LÄS MER

  5. 4. Generation and transmission of mtDNA mutations and their effect on aging

    Författare :Erik Hagström; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Mutations in mtDNA are known to cause neuromuscular diseases and have been associated with several common age-associated diseases as well as being a contributor to the aging process. Despite their importance there are still important aspects of mtDNA inheritance and mtDNA mutations that remain unknown and need to be addressed. LÄS MER

  7. 5. Telomerase activation and its clinical implications in human thyroid tumors

    Författare :Na Wang; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Telomerase is a ribonucleoprotein enzyme. The catalytic and rate-limiting component of telomerase is referred to as telomerase reverse transcriptase (TERT) that plays an important role in telomere maintenance, cell immortalization and malignant transformation. LÄS MER