Sökning: "sequence specific primers"

Visar resultat 26 - 30 av 32 avhandlingar innehållade orden sequence specific primers.

  1. 26. Biomolecular characterization of mumps virus genotypes with varying neurovirulence

    Författare :Tesfaldet Tecle; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Mumps virus is an RNA virus, which belongs to the Rubula virus genus of the family Paramyxoviridae. Mumps is a common childhood infection. Classically, mumps infection presents as parotitis although it is frequently asymptomatic in young children. LÄS MER

  3. 27. Virulence factors and clonal relatedness of enterotoxigenic Escherichia coli (ETEC) isolated from children with diarrhoea in Bolivia

    Författare :Claudia Rodas Miranda; Göteborgs universitet; []
    Nyckelord :Enterotoxigenic Escherichia coli; Virulence factors; Bolivia; Children; Severity of disease; Relatedness;

    Sammanfattning : Enterotoxigenic Escherichia coli (ETEC) is one of the major causes of diarrhoea in children under five years of age in developing countries and in travellers to these settings. To cause disease, ETEC must be able to colonize the small intestine and produce heat-stable enterotoxin (ST) or heat-labile toxin (LT) or both toxins. LÄS MER

  4. 28. B cell transcriptomics and immunoglobulin genetics in rheumatoid arthritis

    Författare :Uta Hardt; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Rheumatoid Arthritis (RA) is a complex autoimmune disease characterized by inflammation of the peripheral joints. The exact disease pathology remains to be elucidated, but it has been hypothesized that autoreactive B cells and autoantibodies play a major role in the etiology. LÄS MER

  5. 29. The cholecystokinin receptor family : molecular cloning and pharmacological characterization

    Författare :Isabelle Nilsson; Dan Larhammar; Linköpings universitet; []
    Nyckelord :MEDICINE; MEDICIN;

    Sammanfattning : Cholecystokinin (CCK) and gastrin are hormones/neurotransmittors of the gastrointestinal tract and central nervous system. The receptors for gastrin and CCK are members of the G protein-coupled receptor family. The aim of this study was to clone and pharmacologically characterize vertebrate and invertebrate CCK receptors and splice variants. LÄS MER

  7. 30. Identification of the common eliminated region (CER1) by the microcell hybrid based 'elimination test'

    Författare :Ying Yang; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Elimination test; common eliminated region 1 CER1 ; 3p21.3; microcell hybrids; tumor suppressor gene; LF lactoferrin ; LIMD1 LIM-domain containing gene 1 ; sequencing; MMCT microcell mediated chromosome transfer ; real time PM methylation;

    Sammanfattning : The aim of elimination test (Et) is to identify tumor antagonizing genes from chromosome regions that are regularly deleted in microcell hybrid (MCH) derived tumors through serial SCID mice passages. Et so far was focused on the short arm of human chromosome 3 (chr 3) due to its frequent deletions in 21 tumor types including renal cell carcinoma (RCC), small cell lung carcinoma (SCLC) and breast cancer (BRC). LÄS MER