Sökning: "Enterotoxigenic Escherichia coli"

Visar resultat 1 - 5 av 17 avhandlingar innehållade orden Enterotoxigenic Escherichia coli.

  1. 1. Presence and viability of enterotoxigenic Escherichia coli (ETEC) in aquatic environments

    Författare :Åsa Lothigius; Göteborgs universitet; []
    Nyckelord :Enterotoxigenic Escherichia coli; ETEC; real-time PCR; aquatic environments; VBNC; resuscitation; infant mouse model;

    Sammanfattning : Enterotoxigenic Escherichia coli (ETEC) is one of the major causes of diarrhoea among children in developing countries and in travelers to these regions. The bacteria are spread via contaminated water and food, and surface and drinking water in developing countries has been found to harbor these organisms. LÄS MER

  3. 2. Whole Genome Sequencing of Enterotoxigenic Escherichia coli

    Författare :Astrid von Mentzer; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; ETEC; whole genome sequencing; evolution; colonization factor; reverse genetics;

    Sammanfattning : Enterotoxigenic Escherichia coli (ETEC) infections are a common cause of diarrhea but little is known about the evolution and genomic composition of ETEC. The main aim of this thesis was to generate a large collection of whole genome sequenced ETEC isolates to study the evolution of such bacteria on a global level and to search for novel colonization factors (CFs) using both classical and cutting-edge genomic techniques. LÄS MER

  4. 3. Virulence factors and clonal relatedness of enterotoxigenic Escherichia coli (ETEC) isolated from children with diarrhoea in Bolivia

    Författare :Claudia Rodas Miranda; Göteborgs universitet; []
    Nyckelord :Enterotoxigenic Escherichia coli; Virulence factors; Bolivia; Children; Severity of disease; Relatedness;

    Sammanfattning : Enterotoxigenic Escherichia coli (ETEC) is one of the major causes of diarrhoea in children under five years of age in developing countries and in travellers to these settings. To cause disease, ETEC must be able to colonize the small intestine and produce heat-stable enterotoxin (ST) or heat-labile toxin (LT) or both toxins. LÄS MER

  5. 4. Studies of Carbohydrate-Binding Proteins from Enterotoxigenic Escherichia coli

    Författare :Lena Jansson; Göteborgs universitet; []
    Nyckelord :Carbohydrate recognition; ETEC colonization factors; CFA I fimbriae; CS6 protein; heat-labile enterotoxin;

    Sammanfattning : Knowledge about the carbohydrate binding specificity of pathogens can give an increased understanding of their virulence strategies, and is also of importance for the development of anti-adhesive therapies and vaccines. Enterotoxigenic Escherichia coli (ETEC) is a well-known causative agent of diarrheal disease. LÄS MER

  7. 5. Structural analyses of carbohydrate receptors for enterotoxins and adhesins of enterotoxigenic Escherichia coli

    Författare :Dani Zalem; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Carbohydrate recognition; glycosphingolipid; diarrheagenic E. coli; ETEC; heat-labile enterotoxin; colonization factor; AB5 toxins;

    Sammanfattning : Carbohydrate-binding proteins expressed by microbes are key determinants in initiating and sustaining infections that account for millions of deaths each year. This thesis fo- cused on proteins integral to infections instigated by enterotoxigenic Escherichia coli (ETEC); estimated as the largest bacterial cause of diarrhea in the world with hundreds of millions of cases each year. LÄS MER