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Visar resultat 1 - 5 av 6 avhandlingar som matchar ovanstående sökkriterier.

1. 1. Fibroblast growth factor-23 and Klotho in bone/mineral and parathyroid disorders

   Författare :Tijana Krajisnik; Tobias E. Larsson; Kenneth B. Jonsson; Östen Ljunggren; Peyman Björklund; Gunnar Sterner; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; calcitriol; chronic kidney disease; CKD; chronic renal failure; fibroblast growth factor 23; fibroblast growth factor-23; FGF23; FGF-23; GalNac-T3; GALNT3; GFR; hyperostosis-hyperphosphatemia syndrome; HHS; Klotho; parathyroid hormone; PTH; hyperparathyroidism; pHPT; sHPT; uremic; vitamin D3; Endocrinology; Endokrinologi; Internal Medicine; invärtesmedicin;

   Sammanfattning : Fibroblast growth factor-23 (FGF23) is a novel, bone-produced hormone that regulates renal phosphate (Pi) reabsorption and calcitriol metabolism. Disorders of mineral and bone metabolism, such as autosomal dominant hypophosphatemic rickets (ADHR) and hyperostosis-hyperphosphatemia syndrome (HHS), witness the importance of well-balanced serum levels of FGF23. LÄS MER

3. 2. Wnt/β-Catenin Signalling in Parathyroid Tumours

   Författare :Peyman Björklund; Gunnar Westin; Göran Åkerström; Tommy Andersson; Uppsala universitet; []
   Nyckelord :Surgery; Hyperparathyroidism; β-catenin; Mutation; Human parathyroid cell line; LRP5; Alternative splicing; Kirurgi;

   Sammanfattning : Primary hyperparathyroidism (pHPT) due to parathyroid tumours with hypersecretion of parathyroid hormone and hypercalcaemia is a common disease with incompletely understood etiology affecting more than 1 % of the population, primarily postmenopausal women. In secondary hyperparathyroidism (sHPT), parathyroid tumours develop in response to calcium and vitamin D deficiency generally in patients with uraemia. LÄS MER

4. 3. Persistent hyperparathyroidism in renal transplant patients

   Författare :Shahriar Akaberi; Njurmedicin; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Kideny transplantation; parathyroidectomy; bone mineral density; DXA; fracture; new onset diabetes after transplantation;

   Sammanfattning : Abstract Disorders in mineral metabolism and secondary hyperparathyroidism (sHPT) are well known complications in patients with chronic kidney disease (CKD). Hyperparathyroidism (HPT) persists in a majority of patients after kidney transplantation (KTx). LÄS MER

5. 4. Vitamin D and its receptor in parathyroid tumors

   Författare :Pamela Correa; Martin Bäckdahl; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Surgery; hyperparathyroidism; loss of heterozygoisty; vitamin D; vitamin D receptor; polymorphism; hydroxylase; genetics; tumorigenesis; Kirurgi; Surgery; Kirurgi; Surgery; kirurgi;

   Sammanfattning : Correa, P. 2002. Vitamin D and its receptor in parathyroid tumors. Acta Universitatis Upsaliensis. LÄS MER

7. 5. Hyperparathyroidism and parathyroidectomy in patients on renal replacement therapy

   Författare :Kerstin Ivarsson; Njurmedicin; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Secondary hyperparathyroidism; End-stage renal disease; Parathyroidectomy; New-onset diabetes after transplantation; Maintenance dialysis; Renal transplantation; Survival; Cardiovascular event; Hip fracture;

   Sammanfattning : Background. Secondary hyperparathyroidism (sHPT) is characterized by over function of the parathyroid glands and disturbances in mineral metabolism as a result of renal failure. It is common among patients with end-stage renal disease (ESRD) and it often persists after successful renal transplantation. LÄS MER