Sökning: "podocytes"

Visar resultat 31 - 34 av 34 avhandlingar innehållade ordet podocytes.

  1. 31. Glomerular expression profiling and novel proteins in normal mouse kidney and adriamycin-induced nephrosis

    Författare :Masatoshi Nukui; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Kidney glomeruli function as high-capacity molecular sieves through which plasma is filtered into the Bowman s space as primary urine. The glomerular filtration barrier is composed of glomerular endothelial cells, the glomerulus basement membrane and the podocyte cell layer. LÄS MER

  3. 32. Nephroprotective effect of the cardiotonic steroid ouabain

    Författare :Ievgeniia Burlaka; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : It has been shown that Na,K-ATPase (NKA) is a signal transducer. Our group described the anti-apoptotic effect of ouabain to the signaling function of NKA. LÄS MER

  4. 33. Nephrin cellular trafficking and intracellular interactions

    Författare :Xiao Li Liu; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Nephrin; signal; missense mutations; trafficking.;

    Sammanfattning : Nephrin is a 180-kDa transmembrane glycoprotein belonging to the immunoglobulin family of cell adhesion molecules. Nephrin has an extracellular part with eight Ig-like motifs, one fibronectin-like domain, a transmembrane region and a short cytoplasmic tail. LÄS MER

  5. 34. Genetic basis of congenital nephrotic syndrome and generation of an animal model

    Författare :Heli Putaala; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Congenital nephrotic syndrome, NPHS1, is a disease highly enriched in Finland with incidence of 1:8200 births. The disease is characterized by massive proteinuria, go % of which is albumin, starting in utero, large placenta, which weighs over 25 % of the child's birth weight, and manifestation of proteinuria soon after birth. LÄS MER