Sökning: "podocytes"
Visar resultat 16 - 20 av 34 avhandlingar innehållade ordet podocytes.
16. Bestrophin-3: Localization and function in normal and injured tissues
Sammanfattning : Bestrophin-3 (Best3) is a protein with multiple functions. It can constitute a calcium-activated chloride channel when overexpressed in cultured cells, but the function of Best3 is not well studied in cells in situ. Recently Best3 protein was suggested to play also cell-protective role. LÄS MER
17. Role of new podocyte-associated proteins in the renal ultrafiltration barrier
Sammanfattning : Chronic kidney disease (CKD) is a major health problem and an economical burden affecting people worldwide. The main causes of CKD are diabetes and hypertension and patient numbers keep increasing. LÄS MER
18. Ultrastructural studies of the blood-urine barrier in proteinuric states
Sammanfattning : The kidneys filter enormous amounts of blood every day, removing excess fluid and waste products while retaining cells and large proteins in the circulation. The podocytes with their foot processes and slit diaphragms (SD) are important components of the renal filter and the barrier function. LÄS MER
19. Podocyte Melanocortin 1 Receptor Mediated Signaling : A potential new target for patients with kidney diseases
Sammanfattning : Treatment of patients with nephrotic syndrome (NS) is currently unspecific and directed at ameliorating the symptoms rather than eliminating the cause. NS is actually a multitude of glomerular diseases characterized by poorly understood disease mechanisms and symptoms that include proteinuria, hypoalbuminemia and edema. LÄS MER
20. Molecular perspectives on glomerular cell physiology in chronic kidney disease
Sammanfattning : Glomerulonephritis is one of the most common causes of chronic kidney disease (CKD) in the world. Recent establishment of guidelines for classification of CKD in five stages has led to increased awareness of the risks of comorbidity and mortality, also in patients with early stages of disease, and the need to further advance our understanding of their pathogenic mechanisms. LÄS MER