Sökning: "patrick"

Visar resultat 16 - 20 av 227 avhandlingar innehållade ordet patrick.

  1. 16. Smoothed Particle Hydrodynamic of Hydraulic Jumps in Spillways

    Författare :Patrick Jonsson; Peter Stansby; Luleå tekniska universitet; []
    Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Strömningslära; Fluid Mechanics;

    Sammanfattning : This thesis focus on the complex natural phenomena of hydraulic jumps using the numerical method Smoothed Particle Hydrodynamics (SPH). A hydraulic jump is highly turbulent and associated with turbulent energy dissipation, air entrainment, surface waves and spray and strong dissipative processes. LÄS MER

  3. 17. Smoothed particle hydrodynamics in hydropower applications : modeling of hydraulic jumps

    Författare :Patrick Jonsson; Gustaf Gustafsson; Luleå tekniska universitet; []
    Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Strömningslära; Fluid Mechanics;

    Sammanfattning : In present thesis, the Lagrangian particle based method Smoothed ParticleHydrodynamics (SPH) is used to model two-dimensional problems associated with hydropower applications such as dam break evolution and hydraulic jumps. In the SPHmethod, the fluid domain is represented by a set of non-connected particles which possess individual material properties such as mass, density, velocity, position and pressure. LÄS MER

  4. 18. Mismatch Repair Deficient Cancer Diagnostic Aspects in Colorectal Cancer and the Role of Urological Cancer in Lynch Syndrome

    Författare :Patrick Joost; Bröstcancer-genetik; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Mismatch repair; Lynch syndrome; immunohistochemistry; microsatellite instability; heterogeneity; cumulative incidence; colorectal cancer; urothelial cancer; prostate cancer; renal cell cancer;

    Sammanfattning : Mismatch repair (MMR) deficiency is carcinogenic and can either have somatic/sporadic causes (i.e. epigenetic silencing or somatic inactivation) or hereditary causes (Lynch syndrome due to a germline mutation in one of the MMR genes ¬- MLH1, MSH2, MSH6, PMS2). LÄS MER

  5. 19. IMPROVED SUPPLY OF DISTRICT HEAT TO HYDRONIC SPACE HEATING SYSTEMS

    Författare :Patrick Lauenburg; Energihushållning; []
    Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; low return temperature; natural circulation; District heating; hydronic space heating;

    Sammanfattning : The studies presented in this thesis concern hydronic space heating systems connected via heat exchangers to a district heating network: referred to as an indirect connection. The objective has been to improve the reliability of district heat supplies and to lower the return temperature from consumer substations. LÄS MER

  7. 20. Characterization of the PGE2 pathway in arthritis and inflammation : mPGES-1 as a therapeutic target

    Författare :Patrick Leclerc; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : The inducible prostaglandin (PG) E2 pathway is defined by the concerted activities of the enzymes cyclooxygenase (COX)-2 and microsomal prostaglandin E synthase (mPGES)-1 in producing PGE2. PGE2 has pro-inflammatory and immunomodulatory functions and is involved in an array of diseases with an autoimmune and chronic inflammatory component, including rheumatoid arthritis (RA). LÄS MER