Sökning: "pancreatic lipase"

Visar resultat 16 - 20 av 20 avhandlingar innehållade orden pancreatic lipase.

  1. 16. Studies on the oxysterol receptor LXRβ : linking cholesterol metabolism to water transport and cell proliferation

    Författare :Chiara Gabbi; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Liver X Receptor β (LXRβ) is a nuclear receptor, belonging to the superfamily of ligand-­activated transcription factors. With its α isoform (LXRα), LXRβ shares more than 78% homology in its amino acid sequence, a common profile of oxysterol ligands and the heterodimerization partner, Retinoid X Receptor. LÄS MER

  3. 17. Adipose and muscle tissue metabolism in cancer cachexia

    Författare :Thorhallur Agustsson; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Background: Loss of adipose and muscle tissue mass is a key feature of cancer cachexia. Weight loss, glucose intolerance, and insulin resistance are seen in patients with pancreatic ductal adenocarcinoma (PDAC). LÄS MER

  4. 18. Novel lipid derivatives for health benefits : synthesis, analysis and effects in diet-induced obese mice

    Författare :Samanthi Madawala; Sveriges lantbruksuniversitet; Sveriges lantbruksuniversitet; []
    Nyckelord :LANTBRUKSVETENSKAPER; AGRICULTURAL SCIENCES;

    Sammanfattning : Obesity is a public health concern and requires effective management with multiple approaches. Dietary supplements of bioactive compounds that can improve fatty acid oxidation and thermogenesis are currently in focus to develop anti-obese food ingredients/nutraceuticals without side-effects. LÄS MER

  5. 19. Omics Techniques Applied to Diabetes Research - Focus on HSL-Null Mice and Clonal β-Cells

    Författare :Celine Fernandez; Molekylär endokrinologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; metabolomics; transcriptomics; treadmill; liver; HSL; cholesterol; proteomics;

    Sammanfattning : Diabetes mellitus is a disease characterized by increased blood glucose levels. For overt type 2 diabetes to develop, both insulin action and insulin secretion must be perturbed. LÄS MER

  7. 20. Role of GPS2 in the regulation of adipocyte fate and function : a multi-omics approach

    Författare :Serena Barilla; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : The escalating prevalence of obesity and its association with comorbidities like insulin resistance and type 2 diabetes have raised the interest in adipose tissue biology and its therapeutic potential. Adipose tissue remodeling during the development of obesity is an important regulator of systemic metabolic homeostasis, and dysfunctional adipose tissue is linked to the risk of developing type 2 diabetes. LÄS MER