Sökning: "intercellular communication"

Visar resultat 26 - 30 av 44 avhandlingar innehållade orden intercellular communication.

  1. 26. Studies on the molecular and functional properties of exosomes in the metastatic prostate cancer bone microenvironment

    Författare :Ioulia Vardaki; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Prostate cancer is the most common cancer type and the second leading cancer related cause of death worldwide in men. Prostate cancer patients initially respond to standard treatment (e.g., hormonal, surgery/irradiation) but about 30% of them will develop resistance and progress to metastatic Castration Resistant Prostate Cancer (mCRPC). LÄS MER

  3. 27. Engineered extracellular vesicles for biomedical applications

    Författare :Dhanu Gupta; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Nature's very own nanoparticle, Extracellular vesicles (EVs), are lipid membrane-enclosed vesicles encapsulated with diverse biomolecules and are actively secreted by all cell types for intercellular communication. The unique properties of EVs, such as stability in circulation, biocompatibility, immune tolerance, and the ability to cross biological barriers, render EVs a next-generation drug delivery tool. LÄS MER

  4. 28. Exosomes from lung and breast milk : regulators of immune responses

    Författare :Patricia Torregrosa Paredes; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Exosomes are key mediators of intercellular communication with the capacity to regulate immune responses, locally and distally. Most knowledge on exosomal function has been gained from exosomes generated from in vitro cell cultures, which has helped define the role of exosomes from specific cell types. LÄS MER

  5. 29. Connexin43 in astroglial gap junctions. Regulation by age, neurotransmitters, GH and IGF-I

    Författare :N David Åberg; Göteborgs universitet; []
    Nyckelord :Connexin43; rat; development; hypophysectomy; primary culture; ; mRNA; gap junction; somatotropin; IGF-I; serotonin; glutamate; ; brain region heterogeneity; calcium wave; astrocyte; astroglial cell; ; gap junctional coupling.;

    Sammanfattning : Connexins form gap junctions that are aqueous pores allowing low-molecular (.... LÄS MER

  7. 30. Pathophysiological role and therapeutic potential of extracellular vesicles in cancer

    Författare :Doste Mamand; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Extracellular vesicles (EVs) are nanosized lipid bilayer vesicles that are endogenously generated through various biogenesis pathways within most cellular entities. Subsequently, they are released into the extracellular milieu to facilitate intercellular communication. LÄS MER