Sökning: "intercellular communication"
Visar resultat 6 - 10 av 44 avhandlingar innehållade orden intercellular communication.
6. Reactive gliosis in the injured brain: The effect of cell communication and Nrf2-mediated cellular defence
Sammanfattning : Stroke and other brain injuries trigger an extensive glial cell response referred to as reactive gliosis. Reactive gliosis is characterized by hypertrophic and proliferating astrocytes, proliferating microglia and NG2-positive cells, which eventually form a bordering glial scar around the damaged area. LÄS MER
7. Mechanistical studies on gap junctions and their role in tumour promotion : structure-activity relationships of polychlorinated biphelyls
Sammanfattning : Chemically induced carcinogenesis is a multi-stage process that can be divided into at least three major stages, initiation, promotion and progression. The promotion stage involves clonal expansion of genetically altered cells (i.e. initiated cells). LÄS MER
8. Calcium signaling in astroglial cells. Noradrenergic effects and regulation
Sammanfattning : Astroglial cells are the most common cell type in the central nervous system and express a wide array of ion channels and neurotransmitter receptors. The cells organize into multicellular networks and exhibit a calcium-based excitability in which receptor-mediated calcium elevations propagate as intercellular waves over considerable distances. LÄS MER
9. Spatial regulation of membrane receptor signaling using DNA origami
Sammanfattning : Juxtracrine signaling between apposing membrane receptors and ligands is an important class of intercellular communication. Much focus has been directed towards studying the biochemical interactions between receptors and ligands, their surface expression levels and signaling activities for driving downstream signaling processes. LÄS MER
10. Two novel combination therapies of glioblastoma multiforme from a Cx43 perspective : studies of in vitro models
Sammanfattning : The group of patients suffering from the malignant brain tumour glioblastoma multiforme (GBM) have a median survival of only about one year. Thus, new treatment strategies are urgently needed. Gap junctions are intercellular channels, permitting intercellular transfer of water soluble substances. LÄS MER