Sökning: "human leukocyte antigen C HLA-C"

Visar resultat 1 - 5 av 6 avhandlingar innehållade orden human leukocyte antigen C HLA-C.

1. 1. Study of the psoriasis proteome and analysis of MHC class I expression and function

   Författare :Lina Carlén; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :Complex disease; psoriasis; proteomics; human leukocyte antigen C HLA-C ; major histocompatibility complex; 2D PAGE; inflammation; skin disease;

   Sammanfattning : Psoriasis is a common inflammatory skin disease affecting approximately 2% of the population in Sweden. Psoriasis displays clinical heterogeneity leading to several different types of manifestations, among them chronic plaque and acute guttate psoriasis. LÄS MER

3. 2. Characterisation of psoriasis lesions by protein expression profiling

   Författare :Lina Carlén; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :Complex disease; psoriasis; proteomics; human leukocyte antigen C HLA-C ; major histocompatibility complex; 2D PAGE; inflammation; skin disease;

   Sammanfattning : Psoriasis is a common inflammatory skin disease affecting approximately 2% of the population in Sweden. Psoriasis displays clinical heterogeneity leading to several different types of manifestations, among them chronic plaque and acute guttate psoriasis, the two most common forms of the disease. LÄS MER

4. 3. Molecular genetic studies of psoriasis susceptibility in 6p21.3

   Författare :Sofia Holm; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :Complex disease; genetic; Psoriasis Susceptibility region 1 PSORS1 ; human leukocyte antigen C HLA-C ; linkage disequilibrium; major histocompatibility complex; single nucleotide polymorphism;

   Sammanfattning : Psoriasis is a common and chronic skin disease with multifactorial background. It affects approximately 2% of the Swedish population and is characterized by inflammatory and scaly lesions. The aetiology of psoriasis is not yet known, however, the genetic contribution to the disease is strong. LÄS MER

5. 4. Umbilical cord blood transplantation : clinical outcome, chimerism development, and in vitro expansion of T-cells for clinical use

   Författare :Sofia Berglund; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :;

   Sammanfattning : Umbilical cord blood (UCB) is an alternative graft source in allogeneic hematopoietic stem cell transplantation (HSCT). The unique advantages with UCB as a stem cell source are found in the permissibility for human leukocyte antigen (HLA)-mismatch, rapid availability, and comparatively risk-free graft collection. LÄS MER

7. 5. HLA genetics in multiple sclerosis

   Författare :Jenny Link; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :;

   Sammanfattning : Multiple sclerosis (MS) is a chronic disease in which both genetic and environmental risk factors contribute to disease susceptibility. MS patients suffer from inflammatory lesions in the central nervous system which results in demyelination of nerve cells, reduced neuronal activity and finally neurodegeneration. LÄS MER