Sökning: "hemochromatosis"

Visar resultat 11 - 13 av 13 avhandlingar innehållade ordet hemochromatosis.

  1. 11. Oxidants and antioxidants in cardiovascular disease

    Författare :Kim Ekblom; Johan Hultdin; Stefan L Marklund; Lars Breimer; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; first-ever acute myocardial infarction; first-ever stroke; bilirubin; iron; HFE genotypes; UGT1A1*28; prospective; risk factor; Cardiovascular medicine; Kardiovaskulär medicin; Epidemiology; Epidemiologi; Clinical Chemistry; klinisk kemi;

    Sammanfattning : Background Cardiovascular diseases, including myocardial infarction and stroke, are the main reason of death in Sweden and Western Europe. High iron stores are believed to produce oxygen radicals, which is the presumed putative mechanism behind lipid peroxidation, atherosclerosis and subsequent cardiovascular disease. LÄS MER

  2. 12. Importance of iron overload and steatosis in patients with chronic liver disease

    Författare :Joel Marmur; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : This thesis deals with the importance of hepatic iron and fat deposition in the context of chronicliver disease, with special focus on the role of the S65C mutation in the hemochromatosis cryptogenic cirrhosis (CC) in patients evaluated for liver transplantation, the expressions of innate and adaptive immunity in non-alcoholic steatohepatitis (NASH), and the role of the ironregulatory hormone hepcidin in dysmetabolic iron overload (DIO). NAFLD is the most common liver disease in the Western world. LÄS MER

  3. 13. Viral and host determinants in hepatitis B

    Författare :Hossein Sendi; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : The outcome of hepatitis B infection is highly variable, ranging from acute disease resulting in the elimination of infection to persistent infection that can lead to cirrhosis or hepatocellular carcinoma. The factors determining the outcome in an individual are not fully known but may be classified into viral and host factors. LÄS MER