Sökning: "genetic polymorphisms"

Visar resultat 26 - 30 av 428 avhandlingar innehållade orden genetic polymorphisms.

  1. 26. Sex steroid metabolism and body composition

    Författare :Charlotte Swanson; Göteborgs universitet; []
    Nyckelord :UDP glucuronosyltranferases; polymorphisms; androgens; glucuronidated androgen metabolites; fat mass; bone; metabolic risk factors; population study;

    Sammanfattning : Background: The bioactive androgens testosterone (T) and dihydrotestosterone (DHT) regulate bone and fat mass in men. The effects of androgens are largely determined by the rate of their synthesis and inactivation. LÄS MER

  3. 27. Aspects of Vitamin D : Prevalence of deficiency and impact on musculoskeletal parameters

    Författare :Anne Björk; Östen Ljunggren; Gunnar Johansson; Andreas Kindmark; Anna Spångeus; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Vitamin D; CYP2R1; Vitamin D receptor Gene; Polymorphisms; Muscle Strength; Endokrinologi och Diabetologi; Endocrinology and Diabetology;

    Sammanfattning : Vitamin D is central in calcium turnover, and adequate levels are important for skeletal health. It is not clear how large contributions from food and sunlight are in Swedish primary care patients, considering the low radiation of UVB in Sweden and fortification of some foods, and whether differences exist between patients of immigrant and Swedish origin. LÄS MER

  4. 28. Genetic studies of depressive symptoms

    Författare :Mårten Jansson; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Depressive Symptoms; Twin; Heritability; Serotonin receptor 2A; Serotonin transporter; MAOA; MAOB; Thrombocyte MAO activity; Linkage Disequilibrium.;

    Sammanfattning : This thesis is focused on depressive symptoms particularly in late fife. Depressive symptoms are associated with serious negative outcomes a greater level of disability and with excess morbidity and mortality. LÄS MER

  5. 29. Hereditary risk factors for stroke in humans - Association studies with emphasis on familial and genotypic factors

    Författare :Håkan Lövkvist; Lund Neurologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; allelic association; candidate genes; case-control; family history; ischemic stroke; polymorphisms.;

    Sammanfattning : Background Stroke is a serious vascular disorder that comprises intracerebral hemorrhages, subarachnoid hemorrhages and ischemic stroke (IS). The etiology of stroke, including hereditary components induced by cellular mechanisms, is therefore a research field of vital importance. LÄS MER

  7. 30. Novel risk factors for atrial fibrillation in an urban population

    Författare :Samuel Adamsson Eryd; Kardiovaskulär forskning - epidemiologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; ceruloplasmin; atrial fibrillation; epidemiology; genetic polymorphisms; intima-media thickness; plasma proteins; red blood cell distribution width; risk factors;

    Sammanfattning : Atrial fibrillation (AF) is the most common sustained cardiac arrhythmia in the general population, and a major cause of morbidity and mortality. Low-grade inflammation, erythrocyte volume variation, and subclinical atherosclerosis have repeatedly been associated with cardiovascular disease, but it remains unclear whether these risk factors are also associated with incident AF. LÄS MER