Sökning: "genetic polymorphisms"
Visar resultat 21 - 25 av 428 avhandlingar innehållade orden genetic polymorphisms.
21. Genetic studies of two inherited human phenotypes : Hearing loss and monoamine oxidase activity
Sammanfattning : This thesis focuses on the identification of genetic factors underlying two inherited human phenotypes: hearing loss and monoamine oxidase activity. Non-syndromic hearing loss segregating in a Swedish family was tested for linkage to 13 previously reported candidate loci for hearing disabilities. LÄS MER
22. THE ANDROGEN RECEPTOR GGN POLYMORPHISM. Genetic and functional analyses
Sammanfattning : Male sex development and reproductive function is regulated by androgens acting via the androgen receptor (AR). The AR harbours two polymorphic repeats of CAG and GGN triplets, encoding glutamines and glycines, respectively. LÄS MER
23. Autoantibodies and genetic variation in rheumatoid arthritis : aspects on susceptibility and disease course
Sammanfattning : Rheumatoid arthritis (RA) is an autoimmune disease characterized by chronic inflammation and subsequent destruction of synovial joints. Although its causes remain largely unknown, a substantial genetic contribution is known to exist. LÄS MER
24. Genetic variation and prostate cancer : population-based association studies in Sweden
Sammanfattning : Prostate cancer constitutes the most common malignancy and the most common cause of cancer‐related death in Swedish men. A large body of evidence suggests that inherited genetic variants contribute to both development and progression of prostate cancer. LÄS MER
25. Candidate Genes for Late Diabetic Complications
Sammanfattning : Diabetes mellitus is a group of metabolic diseases characterized by hyperglycemia resulting from defects in insulin secretion, insulin action, or both. The new WHO criteria for classification of diabetes takes into account also clinical stages dividing the diabetic patients into noninsulin requiring (NIR), insulin requiring for control (IRC) and insulin requiring for survival (IRS) subgroups. LÄS MER