Sökning: "generating function"

Visar resultat 16 - 20 av 242 avhandlingar innehållade orden generating function.

  1. 16. Effects of unloading on skeletal muscle mass and function in man

    Författare :Hans Berg; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Atrophy; bedrest; concentric and isometric and eccentric muscle actions; disuse; electromyography; fatigue; fiber types and size; humans; inactivity; maximal voluntary force; recovery; skeletal muscle cross-sectional area; strength; suspension; tomog;

    Sammanfattning : An experimental human model of skeletal muscle unloading of one lower limb and confined bedrest were employed to quantitate the adaptive responses to 10 days, 4 or 6 wk of unloading in healthy humans on quadricep skeletal muscle mass and function. Muscle cross-sectional area (CSA) was assessed using tomographic imaging (CT, MRI). LÄS MER

  3. 17. Regulation and function of thioredoxin reductase 1 in human tumor cells

    Författare :Markus Selenius; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : The thioredoxin system is a general protein disulfide reductase system present in all organisms. Its function is to maintain an intracellular reducing environment and upholding a defense against reactive oxygen species generated as by-products of aerobic metabolism. LÄS MER

  4. 18. Diversity and function of anti-modified protein autoantibodies in rheumatoid arthritis

    Författare :Peter Sahlström; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Rheumatoid arthritis (RA) is a chronic autoimmune disease particularly affecting synovial joints. Anti-citrullinated protein autoantibodies (ACPA) are detected in the serum of about 2/3 of RA patients and are being used to classify the disease. LÄS MER

  5. 19. Neural stem cells in the spinal cord : identity, function and potential

    Författare :Moa Stenudd; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : A large body of work has been dedicated to understanding and remedying the pathological processes that take place after spinal cord injury. Despite these efforts, treatment options are limited and patients with spinal cord injury are left with life-long disability. LÄS MER

  7. 20. Function and targets of the Urm1/Uba4 conjugation machinery in Drosophila melanogaster

    Författare :Behzad Khoshnood; Caroline Grabbe; Tor Erik Rusten; Umeå universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Drosophila; Urm1; Uba4; MOCS3; Tax; HTLV; Posttranslational modification; ubiquitin-like modifiers; UBL; PTM; JNK; neuromuscular junctions; signaling; molekylärbiologi; Molecular Biology;

    Sammanfattning : Posttranslational modification (PTM) of proteins is essential to maintain homeostasis and viability in all eukaryotic cells. Hence, besides the sequence and 3D folding of a polypeptide, modification by multiple types of PTMs, ranging from small molecular groups to entire protein modules, adds another layer of complexity to protein function and regulation. LÄS MER