Sökning: "HTLV"

Visar resultat 1 - 5 av 7 avhandlingar innehållade ordet HTLV.

  1. 1. Function and targets of the Urm1/Uba4 conjugation machinery in Drosophila melanogaster

    Författare :Behzad Khoshnood; Caroline Grabbe; Tor Erik Rusten; Umeå universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Drosophila; Urm1; Uba4; MOCS3; Tax; HTLV; Posttranslational modification; ubiquitin-like modifiers; UBL; PTM; JNK; neuromuscular junctions; signaling; molekylärbiologi; Molecular Biology;

    Sammanfattning : Posttranslational modification (PTM) of proteins is essential to maintain homeostasis and viability in all eukaryotic cells. Hence, besides the sequence and 3D folding of a polypeptide, modification by multiple types of PTMs, ranging from small molecular groups to entire protein modules, adds another layer of complexity to protein function and regulation. LÄS MER

  3. 2. Cyclic nucleotide signalling systems in vascular smooth muscle cells and immune system cells with special reference to phosphodiesterases PDE3 and PDE4

    Författare :Dag Ekholm; Institutionen för experimentell medicinsk vetenskap; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; HTLV-I; multiple sclerosis; proliferation; phosphorylation; T-lymphocytes; vascular smooth muscle; cloning; protein kinase A; cGMP; cAMP; PDE4; Phosphodiesterase; PDE3; cilostamide; rolipram; Histology; cytochemistry; histochemistry; tissue culture; Histologi; cytokemi; histokemi; vävnadskultur;

    Sammanfattning : The cyclic nucleotide signalling systems are important in vascular smooth muscle and in the immune system, and are of interest from a pharmacological point of view. Drugs which interfere with the cyclic nucleotide levels have profound effects on heart, blood vessels and airways and have actual or potential use in several important diseases, such as heart failure, hypertension, arteriosclerosis, asthma and autoimmune diseases. LÄS MER

  4. 3. The causation of konzo : studies on a paralytic disease in Africa

    Författare :Thorkild Tylleskär; Uppsala universitet; []
    Nyckelord :Spastic paraparesis; konzo; cassava; cyanide; thiocyanate; inorganic sulphate; HTLV-I; MEDICINE; MEDICIN;

    Sammanfattning : Epidemics of a permanent, non-progressive spastic paraparesis with sudden onset hasbeen reported from several rural areas of sub-Saharan Africa. Studies in East Africasuggested an association with dietary cyanide intake from unprocessed cassava. LÄS MER

  5. 4. Prevention of transfusion transmitted infections : donor screening and characteristics of recipient populations

    Författare :Elsa Tynell; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :HTLV-I and II; blood donor screening; transfusion recipients; case-mix; survival rates; false-reactive test results; cost effectiveness;

    Sammanfattning : Minimising the risk for transfusion transmitted infections (TTIs) relies on selection of safe donors, including microbiological screening, and avoidance of unnecessary transfusions. Blood donor screening for HTLV-I and II, was introduced in Sweden in 1994. LÄS MER

  7. 5. Concepts in DNA immunization overcoming viral diversity and enhancing plasmid immunogenicity

    Författare :Erik Rollman; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :HIV; DNA-vaccine; gp 160; GM-CSF; HPV 16 L OBS I; MuLV; prime-boost;

    Sammanfattning : On April 23, 1984, the prominent scientist Robert Gallo held a historical press conference at the Department of Health and Human Services, Washington D.C., USA. He announced that his laboratory at the National Institutes of Health had over the last months isolated a retrovirus named Human T-cell Leukemia Virus type III (HTLV-III). LÄS MER