Sökning: "caco-2 cells"

Visar resultat 16 - 20 av 51 avhandlingar innehållade orden caco-2 cells.

  1. 16. Health Promoting Effects of Bioactive Peptides in Milk - Studies on Cultured Normal Cells and Cancer Cells

    Författare :Catja Freiburghaus; Livsmedelsteknik; []
    Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY;

    Sammanfattning : This thesis concerns the bioactive peptides lactoferricin and ubiquitin and findings suggesting that they have ability to modify the risk of cancer. It is known that components in bovine milk may improve human health and modify the risk of diseases. Examples of such compounds are bioactive peptides, i.e. LÄS MER

  3. 17. Pivotal role of the nuclear receptor PPARgamma in colon epithelial cells

    Författare :Emmelie Å Jansson; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : When symbiosis between the residential intestinal flora and the epithelial cells of the gastrointestinal tract is broken one endpoint may be chronic inflammation, e.g. Inflammatory Bowel Disease (IBD). The disruption of the epithelial lining elicits activation of NF-kappaB and secretion of potent inflammatory mediators. LÄS MER

  4. 18. Staphylococcus aureus alpha-toxin : natural fragments and effects on intestinal epithelial cells

    Författare :Young-Keun Kwak; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Staphylococcus aureus is a human pathogen, commonly found in healthy humans as a part of normal flora. alpha-toxin is thought to be largely responsible for the pathogenesis of the bacterium. LÄS MER

  5. 19. Studies of Vibrio cholerae toxins (zonula occludens toxin and hemagglutinin/protease) and their effects on epithelial cells

    Författare :Zhengyang Wu; Åsa Ljung; Linköpings universitet; []
    Nyckelord :MEDICINE; MEDICIN;

    Sammanfattning : Intestinal epithelium is important for absorption of nutrients and for defense against harmful substances in the gut. The permeability and barrier functions of epithelia are mainly controlled by intercellular tight junctions. LÄS MER

  7. 20. Drug transport and metabolism in in vitro models of the human intestine : By Shamsi D. Raeissi

    Författare :Shamsi D. Raeissi; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Pharmacy; FARMACI; PHARMACY; FARMACI; galenisk farmaci; Pharmaceutics;

    Sammanfattning : The objective of this thesis was to study the mechanisms of drug transport and metabolism in two different in vitro models of the human intestine: monolayers of human intestinal epithelial cell lines and intestinal microsomes. The first part of the thesis shows that Caco-2 cell monolayers are a good model for mechanistic studies of drug transport. LÄS MER