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1. 1. Microfluidic Preparation and Transport of Long DNA using Pillar Arrays

   Författare :Oskar Ström; NanoLund: Centre for Nanoscience; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Microfluidics; Deterministic Lateral Displacement; DNA Separation; Elastic Turbulence; Micro-pillar arrays; DNA Sample Preparation; Lab-on-a chip; elastic waves; Sample Preparation; DNA Isolation; bumper array; Fysicumarkivet A:2023:Ström;

   Sammanfattning : This thesis presents a set of microfluidic tools and experimental studies for preparing (> 20 kbp) for genetic analysisas well as the transport of high-concentration, long-DNA solutions in pillar arrays.Long-DNA sample preparation with conventional gel-based techniques is slow (tens of hours to days) and laborious. LÄS MER