Sökning: "DNA Isolation"
Visar resultat 1 - 5 av 74 avhandlingar innehållade orden DNA Isolation.
1. Microfluidic Preparation and Transport of Long DNA using Pillar Arrays
Sammanfattning : This thesis presents a set of microfluidic tools and experimental studies for preparing (> 20 kbp) for genetic analysisas well as the transport of high-concentration, long-DNA solutions in pillar arrays.Long-DNA sample preparation with conventional gel-based techniques is slow (tens of hours to days) and laborious. LÄS MER
2. DNA-dependent protein kinase in human cells
Sammanfattning : DNA-dependent protein kinase (DNA-PK) is a holoenzyme consisting of a regulatory subunit, the heterodimeric Ku70/86, and a catalytic subunit known as DNA-dependent protein kinase catalytic subunit (DNA-PKcs). DNA-PK takes part in a number of cellular functions including growth control, immunoglobulin gene rearrangement and DNA repair. LÄS MER
3. Sensitive Identification Tools in Forensic DNA Analysis
Sammanfattning : DNA as forensic evidence is valuable in criminal investigations. Implementation of new, sensitive and fast technologies is an important part of forensic genetic research. This thesis aims to evaluate new sensitive methods to apply in forensic DNA analysis including analysis of old skeletal remains. LÄS MER
4. DNA vaccines and bacterial DNA in immunity
Sammanfattning : This thesis describes DNA-based vaccination and the importance of bacterial DNA in different immunological perspectives. Intranasal (i.n.) DNA vaccination utilizing a plasmid encoding the chlamydial heat shock protein 60 (p-hsp-60) generated lower bacterial burden and reduced pathology in the lungs of mice after subsequent infection with C. LÄS MER
5. On Speciation in Birds – Genomic Signatures across Space and Time
Sammanfattning : The process of speciation is a cornerstone in evolutionary biology. In Darwin’s On the Origin of Species, he described how he imagined that a new species would evolve to fill an empty niche. This focus on ecology shifted with Mayr towards the importance of isolation, and for many decades the geographic modes of speciation were debated. LÄS MER