Sökning: "antihypertensive treatment"

Visar resultat 1 - 5 av 48 avhandlingar innehållade orden antihypertensive treatment.

  1. 1. Antihypertensive treatment and endothelial vasodilatory function

    Författare :Bengt von zur Mühlen; Uppsala universitet; []
    Nyckelord :Medical sciences; Hypertension; endothelium; nitric oxide; antihypertensive treatment; MEDICIN OCH VÅRD; MEDICINE; MEDICIN; Medicine; medicin;

    Sammanfattning : The endothelium integrates vascular tone by the synthesis of vasoactive substances secreted abluminally to the underlying vascular smooth muscle. Endothelial function has previously been shown to be impaired in primary, secondary and experimental forms of hypertension. LÄS MER

  2. 2. Effect of antihypertensive treatment at different blood pressure levels

    Författare :Mattias Brunström; Bo Carlberg; Mats Eliasson; Sverre Kjeldsen; Umeå universitet; []
    Nyckelord :MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; blood pressure; hypertension; antihypertensive treatment; cardiovascular disease; randomized controlled trial; systematic review; meta-analysis; standardization;

    Sammanfattning : BackgroundHigh blood pressure is associated with an increased risk of cardiovascular disease and premature death. The shape of association between blood pressure and the risk of cardiovascular events is debated. Some researchers suggest that the association is linear or log-linear, whereas others suggest it is J-shaped. LÄS MER

  3. 3. Pharmacogenetic Studies of Antihypertensive Treatment : With Special Reference to the Renin-Angiotensin-Aldosterone System

    Författare :Lisa Kurland; Heribert Schunkert; Uppsala universitet; []
    Nyckelord :Medical sciences; pharmacogenetics; hypertension; renin-angiotension-aldosterone system; gene polymorphisms; MEDICIN OCH VÅRD; MEDICINE; MEDICIN; Medicine; medicin;

    Sammanfattning : Hypertension is common and constitutes an increased risk of morbidity and mortality of cardiovascular disease. Antihypertensive treatment will reduce this risk; the individual patient's response to treatment, however, is difficult to predict. LÄS MER

  4. 4. Antihypertensive medication in clinical practice : Aspects of patient adherence in treatment

    Författare :Karin I. Kjellgren; Kurt Svärdsudd; Linköpings universitet; []
    Nyckelord :MEDICINE; MEDICIN;

    Sammanfattning : Adherence to antihypertensive drug regimens is a well-documented determinant of blood pressure control. A review of the literature shows that little attention has been paid to how antihypertensive medication is managed in clinical practice. LÄS MER

  5. 5. Pharmacogenomics of Antihypertensive Treatment & Clinical Pharmacological Studies of Digoxin Treatment

    Författare :Pär Hallberg; Håkan Melhus; Ann-Christine Syvänen; Lars Lind; Jiguang Wang; Uppsala universitet; []
    Nyckelord :MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Molecular medicine; pharmacogenomics; irbesartan; atenolol; hypertension; digoxin; RIKS-HIA; atrial fibrillation; heart failure; Molekylärmedicin; Molecular medicine genetics and pathology ; Molekylär medicin genetik och patologi ;

    Sammanfattning : In Part I we found that the CYP2C9 genotype appears to influence the diastolic blood pressure response to the angiotensin II-receptor antagonist irbesartan in patients with hypertension and left ventricular hypertrophy. Those with the *1/*2 genotype (slower metabolism) responded better than those with the *1/*1 genotype (normal metabolism), likely due to a slower elimination of the drug. LÄS MER