Sökning: "adhesive phenotypes"

Visar resultat 6 - 8 av 8 avhandlingar innehållade orden adhesive phenotypes.

1. 6. Host cell adhesion of Plasmodium falciparum-infected erythrocytes

   Författare :Carl Johan Treutiger; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :Plasmodium falciparum; erythrocyte rosetting; cytoadherence; cerebral malaria; PfEMPI; serum proteins; PECAM-I CD31;

   Sammanfattning : Excessive binding of Plasmodium falciparum-infected erythrocytes to the microvascular endothelium (cytoadherence) and to uninfected eryrthrocytes (rosetting) are regarded as key-events in the development of a severe malaria infection. P. falciparum rosetting was confirmed to be associated with the development of cerebral malaria in The Gambia. LÄS MER

3. 7. Genomic and transcripto variation in blood stage Plasmodium falciparum

   Författare :Bobo Mok; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :Antigenic variation; comparative genomic hybridization CGH ; copy number polymorphism CNP ; microarray; P. falciparum; PfEMP1; subtelomeric regions; segmental duplication; switching; var;

   Sammanfattning : Malaria research has entered a postgenomic era since October 2002, when the complete genomic sequence of Plasmodium falciparum strain 3D7 was published. A massive amount of information generated by the P. falciparum genome project has facilitated the development of many novel platforms for profiling different levels of biological aspects. LÄS MER

4. 8. Surface antigens and virulence in Plasmodium falciparum malaria

   Författare :Johan Normark; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :;

   Sammanfattning : Plasmodium falciparum is an intracellular protozoan that may cause severe forms of malaria. It is a major world health hazard and reaps the highest toll among the children and pregnant mothers of the developing world. An Anopheles mosquito vector injects the pathogen when taking a blood meal. LÄS MER