Sökning: "Sweden Stockholm Karolinska Institutet"

Visar resultat 11 - 15 av 373 avhandlingar innehållade orden Sweden Stockholm Karolinska Institutet.

  1. 11. Round window membrane and delivery of biologically active agents into the cochlea

    Författare :Amanj Saber; Mats Ulfendahl; Lars Lundman; Karolinska Institutet; Karolinska Institutet; Sweden Stockholm Karolinska Institutet Department of Clinical Neoruscience; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Round window membrane; sodium hyaluronate; chitosan; local cochlear drug delivery and gene delivery; Oto-rhino-laryngologi; Oto-Rhino-Laryngology; Biology; Biologi; Round window membrane; sodium hyaluronate; chitosan; local cochlear drug delivery and gene delivery;

    Sammanfattning : Establishing efficient methods for local administration of drugs to the inner ear has great clinical relevance for the management of inner ear disorders. However, the administration route remains a critical issue. LÄS MER

  3. 12. Experimental spinal cord injuries : a histopathological, neurological, and pharmacological study in the rat

    Författare :Mia von Euler; Karolinska Institutet; Karolinska Institutet; Sweden STockholm Karolinska Institutet Institutionen för klinisk neurovetenskap; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Sammanfattning : Photochemically-induced ischemic lesions and compression-induced traumatic injuries in the mid-thoracic spinal cord were studied in female rats. The histopathological development of the injuries was found to be similar to that described in other experimental spinal cord injury models and in human post-mortem material. LÄS MER

  4. 13. Parental cancer and children’s well-being : understanding the potential role of psychological stress

    Författare :Chen Ruoqing; Fang Fang; Unnur Valdimarsdóttir; Katja Fall; Kamila Czene; Corinna Bergelt; Sweden Stockholm Karolinska Institutet Institutionen för Medicinsk Epidemiologi och Biostatistik; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Sammanfattning : Early life stress has a major influence on one’s health through the life course. During childhood, early experience may not only affect the normal brain development, but also influence the susceptibility to mental and physical disorders. LÄS MER

  5. 14. Enzymatic studies of alcohol dehydrogenase by a combination of in vitro and in silico methods

    Författare :Mikko Hellgren; Karolinska Institutet; Karolinska Institutet; Sweden Stockholm Karolinska Institutet Department of Medical Biochemistry and Biophysics; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Sammanfattning : The family of alcohol dehydrogenases (ADHs) catalyzes conversions of alcohols, ketons and aldehydes. The early discovery and isolation of ADH (1937) was followed by numerous investigations. It was also the first dimeric enzyme for which the threedimensional structure was determined (1974). LÄS MER

  7. 15. Dementia and its comorbidities : genetic and epigenetic influences

    Författare :Ida K. Karlsson; Karolinska Institutet; Karolinska Institutet; Sweden Stockholm Karolinska Institutet Department of Medical Epidemiology and Biostatistics; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Sammanfattning : Dementia is a multifactorial disorder of late life, characterized by memory deficits, personality changes, and impaired reasoning abilities. There is considerable co-morbidity between dementia, cardiovascular disease (CVD), and late-life depression, but the nature of the associations remains elusive. LÄS MER