Sökning: "Soo Aleman"

Hittade 3 avhandlingar innehållade orden Soo Aleman.

  1. 1. Studies on the efficacy of potent anti-HIV-1 therapy on virological and immunological factors

    Författare :Soo Aleman; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : The aim of this thesis was to assess to which extent treated human immunodeficiency virus type I (HIV-1) infected patients with a seemingly controlled, defined as undetectable plasma HIV-1 RNA levels (< 50 copies/ml), or low-grade viral replication, exhibited pattems in virological and immunological factors which could suggest a continuation of the disease process. We have therefore analysed the kinetics of HIV-1 DNA levels (Papers I and II), the viral evolution (Paper II), the changes in Beta-chemokine levels (Paper 111) and sCD27 levels (Paper IV), and the appearance of drug resistance associated mutations (Paper V) in such patients. LÄS MER

  2. 2. Autoimmune hepatitis : life, death and in-between

    Författare :Åsa Danielsson Borssén; Mårten Werner; Soo Aleman; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; autoimmune hepatitis; autoimmune liver disease; hepatocellular carcinoma; surveillance; pregnancy; pregnancy outcome; cirrhosis; fibrosis; epidemiology; cause of death; medicin; Medicine;

    Sammanfattning : Background Autoimmune hepatitis (AIH) is a chronic autoimmune liver disease that is overrepresented in women (75% of cases). Studies have described a 10-year survival after diagnosis near to that of the general population, but less is known about the long-term survival. LÄS MER

  3. 3. Towards the elimination of hepatitis C : identifying the infected population, and remaining hepatitis C related risks after successful treatment

    Författare :Charlotte Lybeck; Ann-Sofi Duberg; Soo Aleman; Scott Montgomery; Magnus Gottfredsson; Örebro universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; HCV; HCC; epidemiology; MTCT; pregnancy; DAA; OCI;

    Sammanfattning : Chronic Hepatitis C virus (HCV) infection can lead to liver fibrosis and cirrhosis with increased risk of hepatocellular carcinoma (HCC) and liver failure. The World Health Organisation (WHO) has set a goal to eliminate viral hepatitis as a global health threat by 2030. LÄS MER