Sökning: "Sara Af Bjerkén"

Hittade 2 avhandlingar innehållade orden Sara Af Bjerkén.

1. 1. On dopamine neurons : nerve fiber outgrowth and L-DOPA effects

   Författare :Sara af Bjerkén; Ingrid Strömberg; Kathy Steece-Collier; Umeå universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; dopamine; nerve fiber outgrowth; astrocytes; ventral mesencephalon; GDNF; L-DOPA; L-DOPA induced dyskinesia; Neurobiology; Neurobiologi;

   Sammanfattning : Parkinson’s disease is a disorder mainly characterized by progressive degeneration of dopamine producing neurons in the substantia nigra of the midbrain. The most commonly used treatment strategy is to pharmacologically restore the lost function by the administration of the dopaminergic precursor L-DOPA. LÄS MER

3. 2. Deep brain stimulation targeting the caudal zona incerta as a treatment for parkinsonian and essential tremor

   Författare :Rasmus Stenmark Persson; Patric Blomstedt; Sara af Bjerkén; Marwan Hariz; Anders Fytagoridis; Alfonso Fasano; Umeå universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; movement disorders; parkinson s disease; tremor; essential tremor; deep brain stimulation; zona incerta; posterior subthalamic area; Neurology; neurologi; neurokirurgi; Neurosurgery;

   Sammanfattning : Background: Deep brain stimulation (DBS) is used as a treatment for Parkinson’s disease (PD) and Essential tremor (ET) when medications are insufficient. The most common DBS-targets for PD and ET, the subthalamic nucleus (STN) and the ventral intermediate nucleus of the thalamus (Vim) respectively, have certain side effects and limitations. LÄS MER