Sökning: "PGD2"

Visar resultat 1 - 5 av 19 avhandlingar innehållade ordet PGD2.

  1. 1. CC16 in allergy and allergic inflammation

    Författare :Sofi Johansson; Göteborgs universitet; []
    Nyckelord :CC16; CC10; uteroglobin; Clara cell; allergy; asthma; children; allergen; respiratory syncytial virus; T cell; eosinophil; neutrophil; fMLF; PGD2;

    Sammanfattning : Clara cell 16-kDa (CC16) is an anti-inflammatory protein mainly produced in the lung epithelium by Clara cells. Patients with asthma have lower levels of CC16 in bronchoalveolar lavage fluid and serum compared with healthy controls. LÄS MER

  3. 2. On the role of PGD2 metabolites as markers of mast cell activation in asthma

    Författare :Siobhán O'Sullivan; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Prostaglandin D2 (PGD2) is the major cyclooxygenase metabolite of arachidonic acid released after stimulation of mast cells. Prostaglandin D2, itself is a very unstable compound, therefore, quantitative determination of PGD2 is an unreliable indicator of its own endogenous production. LÄS MER

  4. 3. Studies on inhibitory modulation of urinary tract motility

    Författare :Na Guan; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Overactive Bladder (OAB) is a symptom syndrome characterized by urgency and frequency, with or without urge incontinence. Research concerning the mechanisms underlying OAB and finding new inhibitory factor(s) is intensive. LÄS MER

  5. 4. Mast cell activation in response to osmotic and immunological stimulation with focus on release of eicosanoid mediators

    Författare :Magdalena Gulliksson; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Exercise-induced bronchoconstriction; cyclooxygenase; cord blood derived mast cells; mannitol; prostaglandin D2; leukotriene C4; leukotriene E4; histamine and 15-lipoxygenase.;

    Sammanfattning : Mast cells are important in asthma and other inflammatory diseases. Subjects with asthma have been found to have an increased number of mast cells in their airway smooth muscle and this was related to airway sensitivity. LÄS MER

  7. 5. Neuroimmune Interactions of Enteric Neurons and Mast Cells: Friends or Foes?

    Författare :Elin Sand; Neurogastroenterologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; enteric neurons; ischemia; VIP; mast cells; CRF;

    Sammanfattning : Psychological distress or physical strain lead to reduced blood flow in the intestine since other organs are prioritised. One aim of this thesis was to investigate how ischemia followed by reperfusion affects the large intestine and the enteric nervous system (ENS). LÄS MER