Sökning: "Olivia Luige"

Hittade 1 avhandling innehållade orden Olivia Luige.

1. 1. Peptide nucleic acid conjugates as artificial ribonucleases : Cu2+ and Zn2+-dependent PNAzymes

   Författare :Olivia Luige; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :;

   Sammanfattning : Synthetic modified oligonucleotides are gaining momentum as powerful therapeutic tools used in the treatment of life-threatening diseases. Degradation of disease-related RNA sequences is one of the goals achieved with oligonucleotide therapeutics, albeit the currently available technologies rely on the recruitment of endogenous enzymes, RNase H or RISC, limiting the chemical architecture of oligonucleotide drugs. LÄS MER