Sökning: "Niklas Marklund"

Visar resultat 6 - 10 av 11 avhandlingar innehållade orden Niklas Marklund.

1. 6. Plasticity and Inflammation following Traumatic Brain Injury

   Författare :Anders Hånell; Niklas Marklund; Lars Hillered; Nikolaus Plesnila; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Traumatic Brain Injury; plasticity; inflammation; Nogo receptor; EphA4; IL-1β; Neurosurgery; Neurokirurgi; Neuroscience; Neurovetenskap;

   Sammanfattning : Traumatic Brain Injury (TBI) mainly affects young persons in traffic accidents and the elderly in fall accidents. Improvements in the clinical management have significantly improved the outcome following TBI but survivors still suffer from depression, memory problems, personality changes, epilepsy and fatigue. LÄS MER

3. 7. The Neurological Wake-up Test in Neurocritical Care

   Författare :Karin Skoglund; Niklas Marklund; Per Enblad; Tiit Mathiesen; Uppsala universitet; []
   Nyckelord :Intracranial pressure; Cerebral perfusion pressure; Propofol sedation; Wake-up test; stress hormones; intracerebral microdialysis; brain tissue oxygenation; jugular venous oxygenation; Neurokirurgi; Neurosurgery;

   Sammanfattning : The neurological wake-up test, NWT, is a clinical monitoring tool that can be used to evaluate the level of consciousness in patients with traumatic brain injury (TBI) and subarachnoid haemorrhage (SAH) during neurocritical care (NCC). Since patients with severe TBI or SAH are often treated with mechanical ventilation and sedation, the NWT requires that the continuous sedation is interrupted. LÄS MER

4. 8. Surgically Treated Intracerebral Haemorrhage : Pathophysiology and Clinical Aspects

   Författare :Lovisa Tobieson; Niklas Marklund; Bijar Ghafouri; Sandro Rossitti; Peter Zsigmond; Jan Hillman; Mikael Svensson; Linköpings universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

   Sammanfattning : Mortality and morbidity of intracerebral haemorrhage (ICH) is excessively high, and the case fatality rate has not improved in the last decades. Although surgery for ICH can be life-saving, no positive effect on functional outcome has been found in large cohorts of ICH patients. LÄS MER

5. 9. Stem Cell Transplantation in Dorsal Root Injury

   Författare :Carl Trolle; Elena Kozlova; Niklas Marklund; Karin Nordström; Michael Andäng; Mårten Risling; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Sensory Neuron; Regeneration; Spinal Root; Stem Cell; Neuroscience; Neurovetenskap;

   Sammanfattning : After traumatic injuries to the brachial plexus there is a risk that one or more of the spinal roots are torn from the spinal cord, known as avulsion injury. This often leads to paralysis and chronic pain, notoriously difficult to treat with current pharmacotherapy. LÄS MER

7. 10. Short- and long-term consequences of sport-related concussion

   Författare :Fredrik Vedung; Niklas Marklund; Gunnar Antoni; Elna-Marie Larsson; Jakob Johansson; Alexander Olsen; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Sport-related concussion; Soccer; Traumatic brain injury; tau; neuroinflammation; cerebral blood flow; Neurokirurgi; Neurosurgery;

   Sammanfattning : Concussions are common in contact sports. Symptoms such as confusion and/or loss of consciousness following an impact to the head indicate that a sport-related concussion (SRC) has occurred. The symptoms normally resolve within 10-14 days following an SRC in adults although at least 10 % of athletes suffer from prolonged symptoms. LÄS MER