Sökning: "Michael Andäng"

Hittade 2 avhandlingar innehållade orden Michael Andäng.

  1. 1. Expression and function of ribozymes in transgenic mice

    Författare :Michael Andäng; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :hammerhead ribozyme; hairpin ribozyme; transgenic mice; HIV-1; pseudotype virus; cleavage products; cis-cleavage;

    Sammanfattning : Hammerhead and hairpin ribozymes are short RNAs that act as sequence-specific endoribonucleases by cleaving a target RNA after hybridization to complementary sequences. By changing the specific target hybridization sequence of the ribozyme, virtually any RNA can be targeted, making ribozymes a versatile tool for gene down-regulation (knockdown). LÄS MER

  3. 2. Stem Cell Transplantation in Dorsal Root Injury

    Författare :Carl Trolle; Elena Kozlova; Niklas Marklund; Karin Nordström; Michael Andäng; Mårten Risling; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Sensory Neuron; Regeneration; Spinal Root; Stem Cell; Neuroscience; Neurovetenskap;

    Sammanfattning : After traumatic injuries to the brachial plexus there is a risk that one or more of the spinal roots are torn from the spinal cord, known as avulsion injury. This often leads to paralysis and chronic pain, notoriously difficult to treat with current pharmacotherapy. LÄS MER