Sökning: "Membrane protein crystallization"

Visar resultat 6 - 10 av 27 avhandlingar innehållade orden Membrane protein crystallization.

  1. 6. Understanding structure and function of membrane protein transporters

    Författare :Anna-Karin Lundbäck; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Membrane protein transporters are important proteins in the cell, as they maintain different solutes and metabolites at a stable concentration. Numerous diseases can be linked to malfunctioning transporters, which makes them interesting pharmaceutical targets. LÄS MER

  3. 7. Structural Insights at Sub-Ångstrom, Medium and Low Resolution: Crystallization of Trypsin, Bacterioferritin, Photosynthetic Reaction Center, and Photosynthetic Core Complex

    Författare :Weixiao Yuan Wahlgren; Göteborgs universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; protein crystallization; cubic phase; sponge phase; bicelle; trypsin; bacterioferritin; reaction center; core complex; photosynthesis;

    Sammanfattning : The catalytic action of serine proteases depends on the interplay of a nucleophile, a general base and a general acid. The catalytic triad is composed of serine, histidine and aspartate residues. The serine acts as a nucleophile while the histidine plays a dual role as the general base or acid at different steps of the reaction. LÄS MER

  4. 8. Production and Characterisation of Aquaporins and Proton-Translocating Transhydrogenase

    Författare :Mikael Ekvall; Göteborgs universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; aquaporins; transhydrogenase; membrane proteins; x-ray chrystallography; structure; protein production; overproduction;

    Sammanfattning : Dissertation Abstract Water transport in eukaryotic cells is a highly regulated and fine-tuned process. Water channel protein known as aquaporins (AQPs), constitute the main cellular water transport system, preserving water homeostasis by maintaining specific selectivity-mechanisms. LÄS MER

  5. 9. Ultrafast Structural Changes in a Bacterial Photosynthetic Reaction Center probed with XFEL Radiation

    Författare :Robert Dods; Göteborgs universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Photosynthesis; Reaction Center; Time-resolved crystallography; XFEL; membrane protein;

    Sammanfattning : Photosynthesis is the process by which plants and many species of bacteria convert energy from sunlight into chemical energy used to power their metabolism. As these plants and bacteria are eaten, the chemical energy moves up the food chain and thus photosynthesis provides fuel for almost all life on Earth. LÄS MER

  7. 10. Structural biology of integral membrane proteins - From methods to molecular mechanisms

    Författare :Damian Niegowski; Pär Nordlund; Richard Neutze; Stockholms universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; membrane proteins; CorA; magnesium transport; screening; Leukotriene C4 synthase; detergents; Biochemistry; Biokemi; Biochemistry; biokemi;

    Sammanfattning : Membrane proteins are vital components in the cell and crucial for the proliferation of all living organisms. Unfortunately our collective knowledge of structures of membrane proteins is very limited, as compared to the information available on soluble proteins. LÄS MER