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1. 1. Molecular genetic studies of oxidative stress related genes

   Författare :Louise Lyrenäs; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :Gene regulation; oxidative stress; genetic variation; catalase; MGST1; PGES;

   Sammanfattning : This work has focused on the basal characterisation of transcriptional regulation, including genetic variants, in oxidative stress related genes and the possible impact of such variation in cardiovascular disease. The genes under study were catalase and MGST1/PGES where the two former protect from hydrogen peroxide and lipid hydroperoxides respectively and the latter is important in e. LÄS MER